Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intricate processes driving cognitive decline and neurodegeneration. From the gradual loss of neurons and synapses to the formation of protein aggregates characteristic of Alzheimer's disease, each chapter reviews key aspects of brain aging. Chapters dissect the mechanisms driving neuronal loss, synaptic dysfunction, and protein misfolding, shedding light on the intricate interplay of oxidative stress, inflammation, and mitochondrial dysfunction. This book also navigates through strategies for healthy brain aging, from the impact of diet and exercise to the role of cognitive stimulation.
1. Chapter 1. Introduction to the neurobiology of aging - p. 3 2. Chapter 2. Neuronal loss and synaptic dysfunction - p. 23 3. Chapter 3. Protein misfolding and aggregation and its role in dementia with Lewy bodies - p. 43 4. Chapter 4. Oxidative stress and aging - p. 65 5. Chapter 5. Inflammation: chronic inflammation in aging - p. 89 6. Part 2: Factors influencing brain aging - p. P111 7. Chapter 6. Mitochondrial dysfunction and aging - p. 113 8. Chapter 7. Neurotranmitter system in aging - p. 127 9. Chapter 8. Genetic influences on aging and neurodegenerative diseases - p. 145 10. Chapter 9. Environmental and lifestyle factors in brain aging - p. 159 11. Chapter 10. The role of diet in brain health - p. 179 12. Part 3: Interventions and strategies for healthy brain aging - p. P201 13. Chapter 11. Exercise and cognitive function in aging - p. 203 14. Chapter 12. Unlocking cognitive vitality: the interplay of stimulation, sleep, and brain aging - p. 223 15. Chapter 13. Exploring the multifaceted links between comorbidities and cognitive aging - p. 249 16. Chapter 14. Therapeutic approaches to age related cognitive decline and neurodegenerative diseases - p. 267 17. Chapter 15. Exploring promising pharmaceutical candidates for antiaging - p. 287 18. Index - p. 317
Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intricate processes driving cognitive decline and neurodegeneration. From the gradual loss of neurons and synapses to the formation of protein aggregates characteristic of Alzheimer's disease, each chapter reviews key aspects of brain aging. Chapters dissect the mechanisms driving neuronal loss, synaptic dysfunction, and protein misfolding, shedding light on the intricate interplay of oxidative stress, inflammation, and mitochondrial dysfunction. This book also navigates through strategies for healthy brain aging, from the impact of diet and exercise to the role of cognitive stimulation.
1. Chapter 1. Introduction to the neurobiology of aging - p. 3 2. Chapter 2. Neuronal loss and synaptic dysfunction - p. 23 3. Chapter 3. Protein misfolding and aggregation and its role in dementia with Lewy bodies - p. 43 4. Chapter 4. Oxidative stress and aging - p. 65 5. Chapter 5. Inflammation: chronic inflammation in aging - p. 89 6. Part 2: Factors influencing brain aging - p. P111 7. Chapter 6. Mitochondrial dysfunction and aging - p. 113 8. Chapter 7. Neurotranmitter system in aging - p. 127 9. Chapter 8. Genetic influences on aging and neurodegenerative diseases - p. 145 10. Chapter 9. Environmental and lifestyle factors in brain aging - p. 159 11. Chapter 10. The role of diet in brain health - p. 179 12. Part 3: Interventions and strategies for healthy brain aging - p. P201 13. Chapter 11. Exercise and cognitive function in aging - p. 203 14. Chapter 12. Unlocking cognitive vitality: the interplay of stimulation, sleep, and brain aging - p. 223 15. Chapter 13. Exploring the multifaceted links between comorbidities and cognitive aging - p. 249 16. Chapter 14. Therapeutic approaches to age related cognitive decline and neurodegenerative diseases - p. 267 17. Chapter 15. Exploring promising pharmaceutical candidates for antiaging - p. 287 18. Index - p. 317
