Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area.
The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources.
Pharmacogenomics: From Discovery to Clinical Implementation is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. Researchers and graduate students in the related fields of Genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit of the structured approach of the book.
1. Pharmacogenomics - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Contributors - p. Page v 7. List of Illustrations - p. Page x 8. List of Tables - p. Page xi 9. Chapter 1 : Basics of pharmacogenomics - p. Page xi 10. Chapter 2 : Pharmacogenomics in drug metabolism - p. Page 24 11. Chapter 3 : Pharmacogenomics in drug discovery and development - p. Page 50 12. Chapter 4 : Pharmacogenomics testing: An overview - p. Page 87 13. Chapter 5 : Pharmacogenomics and diabetes - p. Page 107 14. Chapter 6 : Pharmacogenomics in cardiovascular diseases - p. Page 130 15. Chapter 7 : Pharmacogenomics in psychiatric diseases - p. Page 158 16. Chapter 8 : Pharmacogenomics in cancer - p. Page 183 17. Chapter 9 : Pharmacogenomics of pulmonary and respiratory diseases - p. Page 216 18. Chapter 10 : Pharmacogenomics in viral diseases - p. Page 246 19. Chapter 11 : Pharmacogenomics in gastroenterology - p. Page 264 20. Chapter 12 : Pharmacogenomics in autoimmune diseases - p. Page 290 21. Chapter 13 : Pharmacogenomics of immunosuppressants - p. Page 317 22. Chapter 14 : Computational and pharmacogenomic resources - p. Page 344 23. Index - p. Page 358
Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area.
The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources.
Pharmacogenomics: From Discovery to Clinical Implementation is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. Researchers and graduate students in the related fields of Genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit of the structured approach of the book.
1. Pharmacogenomics - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Contributors - p. Page v 7. List of Illustrations - p. Page x 8. List of Tables - p. Page xi 9. Chapter 1 : Basics of pharmacogenomics - p. Page xi 10. Chapter 2 : Pharmacogenomics in drug metabolism - p. Page 24 11. Chapter 3 : Pharmacogenomics in drug discovery and development - p. Page 50 12. Chapter 4 : Pharmacogenomics testing: An overview - p. Page 87 13. Chapter 5 : Pharmacogenomics and diabetes - p. Page 107 14. Chapter 6 : Pharmacogenomics in cardiovascular diseases - p. Page 130 15. Chapter 7 : Pharmacogenomics in psychiatric diseases - p. Page 158 16. Chapter 8 : Pharmacogenomics in cancer - p. Page 183 17. Chapter 9 : Pharmacogenomics of pulmonary and respiratory diseases - p. Page 216 18. Chapter 10 : Pharmacogenomics in viral diseases - p. Page 246 19. Chapter 11 : Pharmacogenomics in gastroenterology - p. Page 264 20. Chapter 12 : Pharmacogenomics in autoimmune diseases - p. Page 290 21. Chapter 13 : Pharmacogenomics of immunosuppressants - p. Page 317 22. Chapter 14 : Computational and pharmacogenomic resources - p. Page 344 23. Index - p. Page 358
