Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine.
Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development.
The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences.
1. Chapter 1. Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment - p. 1 2. 1. What Is Precision Medicine? Personalized Medicine Versus Precision Medicine (C. HIzel, P. Hamet, and J. Tremblay) - p. 1 3. 2. Precision Medicine for Population Health (G. Bartlett) - p. 17 4. 3. Conclusion - p. 19 5. Chapter 2. Clinical Next-Generation Sequencing: Enabling Precision Medicine - p. 35 6. Chapter 3. Phenotyping in Precision Medicine - p. 55 7. Chapter 4. Cancer Genetic Screening and Ethical Considerations for Precision Medicine - p. 79 8. Chapter 5. Precision Medicine in Primary Health Care - p. 101 9. Chapter 6. Population Approach to Precision Medicine - p. 115 10. Chapter 7. Regulation of Genomic Testing in the Era of Precision Medicine - p. 129 11. Chapter 8. Image-Based Modeling and Precision Medicine - p. 141 12. Chapter 9. Sharing Outside the Sandbox? The Child’s Right to an Open Data Sharing Future in Genomics and Personalized Medicine - p. 171 13. Chapter 10. Lessons Learned From Cohort Studies, and Hospital-Based Studies and Their Implications in Precision Medicine - p. 187 14. Chapter 11. Clinical Trials in Precision Medicine - p. 209 15. Chapter 12. Time to Educate Physicians and Hospital Staff in Electronic Medical Records for Precision Medicine - p. 217 16. Chapter 13. Computational Approaches in Precision Medicine - p. 233 17. Chapter 14. Handling Big Data in Precision Medicine - p. 251 18. Chapter 15. Trends in Precision Medicine - p. 269 19. Chapter 16. Personalized Medicine: Interdisciplinary Perspective, World Tidal Wave, and Potential Growth for the Emerging Countries - p. 301 20. Index - p. 315
Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine.
Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development.
The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences.
1. Chapter 1. Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment - p. 1 2. 1. What Is Precision Medicine? Personalized Medicine Versus Precision Medicine (C. HIzel, P. Hamet, and J. Tremblay) - p. 1 3. 2. Precision Medicine for Population Health (G. Bartlett) - p. 17 4. 3. Conclusion - p. 19 5. Chapter 2. Clinical Next-Generation Sequencing: Enabling Precision Medicine - p. 35 6. Chapter 3. Phenotyping in Precision Medicine - p. 55 7. Chapter 4. Cancer Genetic Screening and Ethical Considerations for Precision Medicine - p. 79 8. Chapter 5. Precision Medicine in Primary Health Care - p. 101 9. Chapter 6. Population Approach to Precision Medicine - p. 115 10. Chapter 7. Regulation of Genomic Testing in the Era of Precision Medicine - p. 129 11. Chapter 8. Image-Based Modeling and Precision Medicine - p. 141 12. Chapter 9. Sharing Outside the Sandbox? The Child’s Right to an Open Data Sharing Future in Genomics and Personalized Medicine - p. 171 13. Chapter 10. Lessons Learned From Cohort Studies, and Hospital-Based Studies and Their Implications in Precision Medicine - p. 187 14. Chapter 11. Clinical Trials in Precision Medicine - p. 209 15. Chapter 12. Time to Educate Physicians and Hospital Staff in Electronic Medical Records for Precision Medicine - p. 217 16. Chapter 13. Computational Approaches in Precision Medicine - p. 233 17. Chapter 14. Handling Big Data in Precision Medicine - p. 251 18. Chapter 15. Trends in Precision Medicine - p. 269 19. Chapter 16. Personalized Medicine: Interdisciplinary Perspective, World Tidal Wave, and Potential Growth for the Emerging Countries - p. 301 20. Index - p. 315
