The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics.
1. 1. Introduction - p. 227 2. 2. Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis - p. 231 3. 3. Nonatherosclerotic Cardiovascular Disease - p. 245 4. 4. Conclusion - p. 250 5. Chapter 11. Cardiac Involvement in Systemic Lupus Erythematosus - p. 265 6. Chapter 12. Cardiac Involvement in the Antiphospholipid Syndrome - p. 295 7. Chapter 13. Cardiac Involvement in Scleroderma - p. 323 8. Chapter 14. Cardiac Involvement in Systemic Vasculitis - p. 335 9. 1. Introduction - p. 335 10. 2. Pathogenesis of Vasculitides - p. 337 11. 3. Cardiovascular Clinical Manifestations in Vasculitides - p. 339 12. 4. Evolution and Prognostic Factors - p. 357 13. 5. Treatment - p. 357 14. 6. Conclusions - p. 365 15. Chapter 15. Cardiovascular Involvement in Ankylosing Spondylitis - p. 383 16. Chapter 16. Cardiovascular Involvement in Psoriatic Arthritis - p. 409 17. Chapter 17. Cardiovascular Involvement in Primary Sjögren's Syndrome - p. 427 18. Chapter 18. Gout and Heart Disease: A Two-Way Street? - p. 443 19. Chapter 19. Heart Involvement in Osteoarthritis - p. 461 20. 1. Introduction - p. 461 21. 2. Prerequisites: Pathophysiology of Osteoarthritis - p. 474 22. 3. Epidemiologic Data: Osteoarthritis and Cardiovascular Diseases, Two Endemic Diseases - p. 463 23. 4. Association Between Osteoarthritis and Cardiovascular Diseases: Shared Risk Factors - p. 463 24. 5. Association Between Osteoarthritis and Cardiovascular Diseases: Direct Link Beyond CV Risk Factors - p. 471 25. 6. Association Between Osteoarthritis and Cardiovascular Diseases: an Epiphenomenon? - p. 471 26. 7. New Perspectives: The Role of Microbiota - p. 472 27. 8. Conclusions - p. 473 28. Chapter 20. Cardiac Effects of Antirheumatic Drugs - p. 489 29. 1. Introduction - p. 489 30. 2. Atherosclerosis and Metabolic Syndrome - p. 490 31. 3. Other Heart Diseases - p. 507 32. 4. Recommendations for Cardiovascular Risk Management in Arthritides - p. 509 33. 5. Conclusions - p. 510 34. Index - p. 531
The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics.
1. 1. Introduction - p. 227 2. 2. Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis - p. 231 3. 3. Nonatherosclerotic Cardiovascular Disease - p. 245 4. 4. Conclusion - p. 250 5. Chapter 11. Cardiac Involvement in Systemic Lupus Erythematosus - p. 265 6. Chapter 12. Cardiac Involvement in the Antiphospholipid Syndrome - p. 295 7. Chapter 13. Cardiac Involvement in Scleroderma - p. 323 8. Chapter 14. Cardiac Involvement in Systemic Vasculitis - p. 335 9. 1. Introduction - p. 335 10. 2. Pathogenesis of Vasculitides - p. 337 11. 3. Cardiovascular Clinical Manifestations in Vasculitides - p. 339 12. 4. Evolution and Prognostic Factors - p. 357 13. 5. Treatment - p. 357 14. 6. Conclusions - p. 365 15. Chapter 15. Cardiovascular Involvement in Ankylosing Spondylitis - p. 383 16. Chapter 16. Cardiovascular Involvement in Psoriatic Arthritis - p. 409 17. Chapter 17. Cardiovascular Involvement in Primary Sjögren's Syndrome - p. 427 18. Chapter 18. Gout and Heart Disease: A Two-Way Street? - p. 443 19. Chapter 19. Heart Involvement in Osteoarthritis - p. 461 20. 1. Introduction - p. 461 21. 2. Prerequisites: Pathophysiology of Osteoarthritis - p. 474 22. 3. Epidemiologic Data: Osteoarthritis and Cardiovascular Diseases, Two Endemic Diseases - p. 463 23. 4. Association Between Osteoarthritis and Cardiovascular Diseases: Shared Risk Factors - p. 463 24. 5. Association Between Osteoarthritis and Cardiovascular Diseases: Direct Link Beyond CV Risk Factors - p. 471 25. 6. Association Between Osteoarthritis and Cardiovascular Diseases: an Epiphenomenon? - p. 471 26. 7. New Perspectives: The Role of Microbiota - p. 472 27. 8. Conclusions - p. 473 28. Chapter 20. Cardiac Effects of Antirheumatic Drugs - p. 489 29. 1. Introduction - p. 489 30. 2. Atherosclerosis and Metabolic Syndrome - p. 490 31. 3. Other Heart Diseases - p. 507 32. 4. Recommendations for Cardiovascular Risk Management in Arthritides - p. 509 33. 5. Conclusions - p. 510 34. Index - p. 531
