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Transport Proteins, Volume 123, provides the latest information on the two major groups of transport proteins, those that carry molecules to different locations within a cell or organism and those that carry molecules across otherwise impermeable membranes. Chapters in the updated release include Biology of Iron Transport: Ferroportin, Transport of transition metals across biological membranes, The effect of sport and physical activity on transport proteins: implications for cancer prevention and control, Structural rearrangement in polyketide synthase for improvement its bio-physicochemical properties, Autophagy Proteins and its Homeostasis in Cellular Environment, and much more.

  • Integrates experimental and computational methods for studying the structure and function of transport proteins and their implication in drug design
  • Contains timely chapters written by well-renowned authorities in their field
  • Includes a high number of top quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students

1. Cover image - p. ii 2. Title page - p. ii 3. Table of Contents - p. iii 4. Advances in Protein Chemistry and Structural Biology - p. i 5. Copyright - p. iv 6. Contributors - p. ix 7. Chapter One. Biology of the iron efflux transporter, ferroportin - p. 1 8. Chapter Two. The effect of sport and physical activity on transport proteins: implications for cancer prevention and control - p. 17 9. Chapter Three. Cancer bioenergetics as emerging holistic cancer theory: the role of metabolic fluxes and transport proteins involved in metabolic pathways in the pathogenesis of malignancies. State-of-the-art and future prospects - p. 27 10. Chapter Four. Investigating mutations at the hotspot position of the ERBB2 and screening for the novel lead compound to treat breast cancer – a computational approach - p. 49 11. Chapter Five. Autophagy proteins and its homeostasis in cellular environment - p. 73 12. Chapter Six. Expression of placental glucose transporter proteins in pregnancies complicated by fetal growth disorders - p. 95 13. Chapter Seven. The role of transferrins and iron-related proteins in brain iron transport: applications to neurological diseases - p. 133 14. Chapter Eight. ABCG: a new fold of ABC exporters and a whole new bag of riddles! - p. 163 15. Chapter Nine. Serum albumin: clinical significance of drug binding and development as drug delivery vehicle - p. 193 16. Chapter Ten. PTR2/POT/NPF transporters: what makes them tick? - p. 219 17. Chapter Eleven. Network analysis of transcriptomics data for the prediction and prioritization of membrane-associated biomarkers for idiopathic pulmonary fibrosis (IPF) by bioinformatics approach - p. 241

Descripcion
Descripción

Transport Proteins, Volume 123, provides the latest information on the two major groups of transport proteins, those that carry molecules to different locations within a cell or organism and those that carry molecules across otherwise impermeable membranes. Chapters in the updated release include Biology of Iron Transport: Ferroportin, Transport of transition metals across biological membranes, The effect of sport and physical activity on transport proteins: implications for cancer prevention and control, Structural rearrangement in polyketide synthase for improvement its bio-physicochemical properties, Autophagy Proteins and its Homeostasis in Cellular Environment, and much more.

  • Integrates experimental and computational methods for studying the structure and function of transport proteins and their implication in drug design
  • Contains timely chapters written by well-renowned authorities in their field
  • Includes a high number of top quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students

1. Cover image - p. ii 2. Title page - p. ii 3. Table of Contents - p. iii 4. Advances in Protein Chemistry and Structural Biology - p. i 5. Copyright - p. iv 6. Contributors - p. ix 7. Chapter One. Biology of the iron efflux transporter, ferroportin - p. 1 8. Chapter Two. The effect of sport and physical activity on transport proteins: implications for cancer prevention and control - p. 17 9. Chapter Three. Cancer bioenergetics as emerging holistic cancer theory: the role of metabolic fluxes and transport proteins involved in metabolic pathways in the pathogenesis of malignancies. State-of-the-art and future prospects - p. 27 10. Chapter Four. Investigating mutations at the hotspot position of the ERBB2 and screening for the novel lead compound to treat breast cancer – a computational approach - p. 49 11. Chapter Five. Autophagy proteins and its homeostasis in cellular environment - p. 73 12. Chapter Six. Expression of placental glucose transporter proteins in pregnancies complicated by fetal growth disorders - p. 95 13. Chapter Seven. The role of transferrins and iron-related proteins in brain iron transport: applications to neurological diseases - p. 133 14. Chapter Eight. ABCG: a new fold of ABC exporters and a whole new bag of riddles! - p. 163 15. Chapter Nine. Serum albumin: clinical significance of drug binding and development as drug delivery vehicle - p. 193 16. Chapter Ten. PTR2/POT/NPF transporters: what makes them tick? - p. 219 17. Chapter Eleven. Network analysis of transcriptomics data for the prediction and prioritization of membrane-associated biomarkers for idiopathic pulmonary fibrosis (IPF) by bioinformatics approach - p. 241

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