Year Book of Pulmonary Diseases 2012

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 2 4. Asthma, Allergy and Cystic Fibrosis - p. 5 5. Asthma - p. 5 6. Two Days of Dexamethasone Versus 5 Days of Prednisone in the Treatment of Acute Asthma: A Randomized Controlled Trial - p. 5 7. Nebulized Budesonide Added to Standard Pediatric Emergency Department Treatment of Acute Asthma: A Randomized, Double-blind Trial - p. 6 8. Tiotropium improves lung function in patients with severe uncontrolled asthma: A randomized controlled trial - p. 7 9. Point: Efficacy of Bronchial Thermoplasty for Patients With Severe Asthma. Is There Sufficient Evidence? Yes - p. 8 10. Internet-based tapering of oral corticosteroids in severe asthma: a pragmatic randomised controlled trial - p. 9 11. Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial - p. 10 12. Daily exhaled nitric oxide measurements and asthma exacerbations in children - p. 11 13. An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (Fe NO) for Clinical Applications - p. 12 14. Age and Risks of FDA-Approved Long-Acting β 2-Adrenergic Receptor Agonists - p. 13 15. Efficacy of budesonide/formoterol pressurized metered-dose inhaler versus budesonide pressurized metered-dose inhaler alone in Hispanic adults and adolescents with asthma: a randomized, controlled trial - p. 14 16. Fluticasone furoate demonstrates efficacy in patients with asthma symptomatic on medium doses of inhaled corticosteroid therapy: an 8-week, randomised, placebo-controlled trial - p. 15 17. Reslizumab for Poorly Controlled, Eosinophilic Asthma: A Randomized, Placebo-Controlled Study - p. 16 18. Association between childhood asthma and ADHD symptoms in adolescence – a prospective population-based twin study - p. 17 19. Cystic Fibrosis - p. 18 20. Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation - p. 18 21. A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation - p. 19 22. Comparative Efficacy and Safety of 4 Randomized Regimens to Treat Early Pseudomonas aeruginosa Infection in Children With Cystic Fibrosis - p. 20 23. Improved treatment response to dornase alfa in cystic fibrosis patients using controlled inhalation - p. 21 24. Chronic Obstructive Pulmonary Disease - p. 22 25. Lifetime risk of developing chronic obstructive pulmonary disease: a longitudinal population study - p. 22 26. Geographic Isolation and the Risk for Chronic Obstructive Pulmonary Disease–Related Mortality: A Cohort Study - p. 23 27. Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease: Incidence and Predicting Factors - p. 24 28. Racial Differences in Quality of Life in Patients With COPD - p. 25 29. Early-Onset Chronic Obstructive Pulmonary Disease Is Associated with Female Sex, Maternal Factors, and African American Race in the COPDGene Study - p. 26 30. The Progression of Chronic Obstructive Pulmonary Disease Is Heterogeneous: The Experience of the BODE Cohort - p. 27 31. The Chronic Bronchitic Phenotype of COPD: An Analysis of the COPDGene Study - p. 28 32. Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Identification of Biologic Clusters and Their Biomarkers - p. 29 33. Validation of a Novel Risk Score for Severity of Illness in Acute Exacerbations of COPD - p. 30 34. Effect of an action plan with ongoing support by a case manager on exacerbation-related outcome in patients with COPD: a multicentre randomised controlled trial - p. 31 35. Azithromycin for Prevention of Exacerbations of COPD - p. 32 36. Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled trials - p. 33 37. Risk of fractures with inhaled corticosteroids in COPD: systematic review and meta-analysis of randomised controlled trials and observational studies - p. 34 38. The Impact of Anxiety and Depression on Outcomes of Pulmonary Rehabilitation in Patients With COPD - p. 35 39. Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study - p. 36 40. Factors Associated With Bronchiectasis in Patients With COPD - p. 37 41. Lung Cancer - p. 38 42. Epidemiology of Lung Cancer - p. 38 43. Cancer Statistics, 2011: The Impact of Eliminating Socioeconomic and Racial Disparities on Premature Cancer Deaths - p. 38 44. Lung Cancer Risk Prediction: Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial Models and Validation - p. 39 45. Incorporation of a Genetic Factor into an Epidemiologic Model for Prediction of Individual Risk of Lung Cancer: The Liverpool Lung Project - p. 40 46. Human Immunodeficiency Virus–Associated Primary Lung Cancer in the Era of Highly Active Antiretroviral Therapy: A Multi-Institutional Collaboration - p. 41 47. Serum B Vitamin Levels and Risk of Lung Cancer - p. 42 48. Tobacco-Related Issues - p. 43 49. Quitting Smoking Among Adults — United States, 2001–2010 - p. 43 50. Treating Smokers in the Health Care Setting - p. 44 51. Lung Cancer Screening - p. 45 52. Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening - p. 45 53. Screening by Chest Radiograph and Lung Cancer Mortality: The Prostate, Lung, Colorectal, and Ovarian (PLCO) Randomized Trial - p. 46 54. Baseline Characteristics of Participants in the Randomized National Lung Screening Trial - p. 47 55. Identification of Chronic Obstructive Pulmonary Disease in Lung Cancer Screening Computed Tomographic Scans - p. 48 56. Diagnostic Evaluation - p. 49 57. Seventh Edition of the Cancer Staging Manual and Stage Grouping of Lung Cancer: Quick Reference Chart and Diagrams - p. 49 58. Mediastinoscopy vs Endosonography for Mediastinal Nodal Staging of Lung Cancer: A Randomized Trial - p. 50 59. Population-Based Risk for Complications After Transthoracic Needle Lung Biopsy of a Pulmonary Nodule: An Analysis of Discharge Records - p. 51 60. Cumulative Radiation Dose From Medical Imaging Procedures in Patients Undergoing Resection for Lung Cancer - p. 52 61. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma - p. 53 62. Trends in Stage Distribution for Patients with Non-small Cell Lung Cancer: A National Cancer Database Survey - p. 54 63. Variability of Lung Tumor Measurements on Repeat Computed Tomography Scans Taken Within 15 Minutes - p. 55 64. Lung Cancer Treatment - p. 56 65. Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer - p. 56 66. Targeting Anaplastic Lymphoma Kinase in Lung Cancer - p. 57 67. Treatment of Non–Small-Cell Lung Cancer with Erlotinib or Gefitinib - p. 58 68. Survival Following Lobectomy and Limited Resection for the Treatment of Stage I Non-small Cell Lung Cancer ≤1 cm in Size: A Review of SEER Data - p. 59 69. Lung Cancer in Chronic Obstructive Pulmonary Disease: Enhancing Surgical Options and Outcomes - p. 60 70. Surgeon Specialty and Long-Term Survival After Pulmonary Resection for Lung Cancer - p. 61 71. Molecular Approach to Lung Cancer - p. 62 72. New driver mutations in non-small-cell lung cancer - p. 62 73. Frequency of EGFR and KRAS Mutations in Lung Adenocarcinomas in African Americans - p. 63 74. Prognostic and Predictive Gene Signature for Adjuvant Chemotherapy in Resected Non–Small-Cell Lung Cancer - p. 64 75. Pleural, Interstitial Lung and Pulmonary Vascular Disease - p. 65 76. Pulmonary Vascular Disease - p. 65 77. A noninvasive algorithm to exclude pre-capillary pulmonary hypertension - p. 65 78. Usefulness of Serial N-Terminal Pro–B-Type Natriuretic Peptide Measurements for Determining Prognosis in Patients With Pulmonary Arterial Hypertension - p. 66 79. Tricuspid Annular Plane Systolic Excursion Is a Robust Outcome Measure in Systemic Sclerosis-associated Pulmonary Arterial Hypertension - p. 67 80. Race and Sex Differences in Response to Endothelin Receptor Antagonists for Pulmonary Arterial Hypertension - p. 68 81. Long-term efficacy of bosentan in treatment of pulmonary arterial hypertension in children - p. 69 82. Long-term effects of inhaled treprostinil in patients with pulmonary arterial hypertension: The TReprostinil sodium Inhalation Used in the Management of Pulmonary arterial Hypertension (TRIUMPH) study open-label extension - p. 70 83. Long-term Treatment With Sildenafil Citrate in Pulmonary Arterial Hypertension: The SUPER-2 Study - p. 71 84. Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Target of Phosphodiesterase-5 Inhibition in a 1-Year Study - p. 72 85. Intensive Care Unit Management of Patients with Severe Pulmonary Hypertension and Right Heart Failure - p. 73 86. Interstitial Lung Disease - p. 74 87. Proinflammatory and Antiinflammatory Cytokine Levels in Complicated and Noncomplicated Parapneumonic Pleural Effusions - p. 74 88. Automated Quantification of High-Resolution CT Scan Findings in Individuals at Risk for Pulmonary Fibrosis - p. 75 89. Ascertainment of Individual Risk of Mortality for Patients with Idiopathic Pulmonary Fibrosis - p. 76 90. Delayed Access and Survival in Idiopathic Pulmonary Fibrosis: A Cohort Study - p. 77 91. Gastroesophageal Reflux Therapy Is Associated with Longer Survival in Patients with Idiopathic Pulmonary Fibrosis - p. 78 92. Pleural Disease - p. 79 93. Community - Acquired Pneumonia - p. 80 94. Validation of the Infectious Diseases Society of America/American Thoratic Society Minor Criteria for Intensive Care Unit Admission in Community-Acquired Pneumonia Patients Without Major Criteria or Contraindications to Intensive Care Unit Care - p. 80 95. Severity assessment tools to guide ICU admission in community-acquired pneumonia: systematic review and meta-analysis - p. 81 96. Low CURB-65 is of limited value in deciding discharge of patients with community-acquired pneumonia - p. 82 97. Procalcitonin Algorithms for Antibiotic Therapy Decisions: A Systematic Review of Randomized Controlled Trials and Recommendations for Clinical Algorithms - p. 83 98. Inflammatory responses predict long-term mortality risk in community-acquired pneumonia - p. 84 99. Dexamethasone and length of hospital stay in patients with community-acquired pneumonia: a randomised, double-blind, placebo-controlled trial - p. 85 100. Hospital-reported Data on the Pneumonia Quality Measure “Time to First Antibiotic Dose” Are Not Associated With Inpatient Mortality: Results of a Nationwide Cross-sectional Analysis - p. 86 101. Epidemiology, Antibiotic Therapy, and Clinical Outcomes in Health Care–Associated Pneumonia: A UK Cohort Study - p. 87 102. Patterns of Antimicrobial Use for Respiratory Tract Infections in Older Residents of Long-Term Care Facilities - p. 88 103. How deadly is seasonal influenza-associated pneumonia? The German Competence Network for Community-Acquired Pneumonia - p. 89 104. British Thoracic Society adult community acquired pneumonia audit 2009/10 - p. 90 105. Long-term use of thiazolidinediones and the associated risk of pneumonia or lower respiratory tract infection: systematic review and meta-analysis - p. 91 106. The Spectrum of Pneumococcal Empyema in Adults in the Early 21st Century - p. 92 107. Lung Transplantation - p. 93 108. Predictors of Acute Rejection After Lung Transplantation - p. 93 109. Timing of basiliximab induction and development of acute rejection in lung transplant patients - p. 94 110. The protective role of laparoscopic antireflux surgery against aspiration of pepsin after lung transplantation - p. 95 111. High Levels of Mannose-Binding Lectin Are Associated With Poor Outcomes After Lung Transplantation - p. 96 112. Circulating Fibrocytes Correlate With Bronchiolitis Obliterans Syndrome Development After Lung Transplantation: A Novel Clinical Biomarker - p. 97 113. Cytomegalovirus Replication Within the Lung Allograft Is Associated With Bronchiolitis Obliterans Syndrome - p. 98 114. Survival Determinants in Lung Transplant Patients With Chronic Allograft Dysfunction - p. 99 115. Comparison of Hospitalized Solid Organ Transplant Recipients and Nonimmunocompromised Patients With Pandemic H1N1 Infection: A Retrospective Cohort Study - p. 100 116. Pneumonia Complicating Pandemic (H1N1) 2009: Risk Factors, Clinical Features, and Outcomes - p. 101 117. Invasive Fungal Infections in Lung Transplant Recipients Not Receiving Routine Systemic Antifungal Prophylaxis: 12-Year Experience at a University Lung Transplant Center - p. 102 118. Increased Serum Vitamin A and E Levels After Lung Transplantation - p. 103 119. Ocular complications in patients with lung transplants - p. 104 120. Outcomes After Lung Transplantation and Practices of Lung Transplant Programs in the United States Regarding Hepatitis C Seropositive Recipients - p. 105 121. Impact of Anastomotic Techniques on Airway Complications After Lung Transplant - p. 106 122. Lung transplantation in children with idiopathic pulmonary arterial hypertension: An 18-year experience - p. 107 123. Sleep Disorders - p. 108 124. Diagnosis of Sleep-Disordered Breathing - p. 108 125. An Integrated Health-Economic Analysis of Diagnostic and Therapeutic Strategies in the Treatment of Moderate-to-Severe Obstructive Sleep Apnea - p. 108 126. Therapeutic Decision-making for Sleep Apnea and Hypopnea Syndrome Using Home Respiratory Polygraphy: A Large Multicentric Study - p. 109 127. Epidemiology of Sleep-Disordered Breathing - p. 110 128. Consequences of Sleep-Disordered Breathing - p. 111 129. Cheyne–Stokes respiration and obstructive sleep apnoea are independent risk factors for malignant ventricular arrhythmias requiring appropriate cardioverter-defibrillator therapies in patients with congestive heart failure - p. 111 130. Obstructive sleep apnoea: a stand-alone risk factor for chronic kidney disease - p. 112 131. Obstructive Sleep Apnea: Brain Structural Changes and Neurocognitive Function before and after Treatment - p. 113 132. Sleep-Disordered Breathing, Hypoxia, and Risk of Mild Cognitive Impairment and Dementia in Older Women - p. 114 133. CPAP Treatment and Benefits - p. 115 134. Continuous Positive Airway Pressure in Severe Obstructive Sleep Apnea Reduces Pain Sensitivity - p. 115 135. Early treatment of obstructive apnoea and stroke outcome: a randomised controlled trial - p. 116 136. Effects of Continuous Positive Airway Pressure Therapy Withdrawal in Patients with Obstructive Sleep Apnea: A Randomized Controlled Trial - p. 117 137. Non-CPAP Treatment of Sleep-Disordered Breathing - p. 118 138. Pediatric Sleep-Disordered Breathing - p. 119 139. Non-Pulmonary Sleep - p. 120 140. A Brief Sleep Intervention Improves Outcomes in the School Entry Year: A Randomized Controlled Trial - p. 120 141. Efficacy of Brief Behavioral Treatment for Chronic Insomnia in Older Adults - p. 121 142. Increasing Walking and Bright Light Exposure to Improve Sleep in Community-Dwelling Persons with Alzheimer's Disease: Results of a Randomized, Controlled Trial - p. 122 143. Prospective Evaluation of Consultant Surgeon Sleep Deprivation and Outcomes in More Than 4000 Consecutive Cardiac Surgical Procedures - p. 123 144. Quantification of sleep behavior and of its impact on the cross-talk between the brain and peripheral metabolism - p. 124 145. Sleep Disorders, Health, and Safety in Police Officers - p. 125 146. Sleep Duration or Bedtime? Exploring the Relationship between Sleep Habits and Weight Status and Activity Patterns - p. 126 147. The Effect of Melatonin, Magnesium, and Zinc on Primary Insomnia in Long-Term Care Facility Residents in Italy: A Double-Blind, Placebo-Controlled Clinical Trial - p. 127 148. Critical Care Medicine - p. 128 149. Ventilator Weaning - p. 128 150. Implementing Early Mobilization Interventions in Mechanically Ventilated Patients in the ICU - p. 128 151. A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV) - p. 129 152. Ventilator-Associated Pneumonia - p. 130 153. Acute Respiratory Disorder Syndrome - p. 131 154. A Description of Intraoperative Ventilator Management in Patients with Acute Lung Injury and the Use of Lung Protective Ventilation Strategies - p. 131 155. Comparison of airway pressure release ventilation to conventional mechanical ventilation in the early management of smoke inhalation injury in swine - p. 132 156. Noninvasive versus invasive ventilation for acute respiratory failure in patients with hematologic malignancies: A 5-year multicenter observational survey - p. 133 157. Acute Respiratory Failure - p. 134 158. Airway Management - p. 135 159. GlideScope videolaryngoscope vs. Macintosh direct laryngoscope for intubation of morbidly obese patients: a randomized trial - p. 135 160. Airway challenges in critical care - p. 136 161. Anaphylaxis pathogenesis and treatment - p. 137 162. Imaging and Monitoring in the ICU - p. 138 163. Cardiopulmonary Interactions - p. 139 164. Prognostic implications of arterial blood gases in acute decompensated heart failure - p. 139 165. Incident Stroke and Mortality Associated With New-Onset Atrial Fibrillation in Patients Hospitalized With Severe Sepsis - p. 140 166. Pulmonary Hypertension in the ICU - p. 141 167. Trauma Issues - p. 142 168. Costs of Postoperative Sepsis: The Business Case for Quality Improvement to Reduce Postoperative Sepsis in Veterans Affairs Hospitals - p. 142 169. Atelectasis as a Cause of Postoperative Fever: Where Is the Clinical Evidence? - p. 143 170. A Method to Detect Occult Pneumothorax With Chest Radiography - p. 144 171. A comparative study of two- versus one-lung ventilation for needlescopic bleb resection - p. 145 172. Miscellaneous - p. 146 173. “CAN WE FEED?” A Mnemonic to Merge Nutrition and Intensive Care Assessment of the Critically Ill Patient - p. 146 174. A Model for Increasing Palliative Care in the Intensive Care Unit: Enhancing Interprofessional Consultation Rates and Communication - p. 147 175. Impact of Nonphysician Staffing on Outcomes in a Medical ICU - p. 148 176. A Prospective Observational Study of Physician Handoff for Intensive-Care-Unit-to-Ward Patient Transfers - p. 149 177. Association of ICU or Hospital Admission With Unintentional Discontinuation of Medications for Chronic Diseases - p. 150 178. Diabetes Is Not Associated With Increased Mortality in Emergency Department Patients With Sepsis - p. 151 179. How do I investigate septic transfusion reactions and blood donors with culture-positive platelet donations? - p. 152