Chronic Renal Disease, Second Edition, comprehensively investigates the physiology, pathophysiology, treatment and management of chronic kidney disease (CKD). This translational reference takes an in-depth look at CKD with no coverage of dialysis or transplantation. Chapters are devoted to the scientific investigation of chronic kidney disease, the most common problems faced by nephrologists in the management of chronic kidney disease, specific illnesses in the CKD framework, and how the management of CKD in a polycystic kidney disease patient differs from other CKD patients. This award-winning reference features a series of case studies, covering both clinical aspects and pathophysiology.
Questions are open ended, progressively more difficult, and repetitive across different patient clinical problems and different chapters. The cases and questions included will be useful for medical students, residency board reviews, and clinician teaching or conference preparation.
1. Part I. Introduction - p. xxi 2. Chapter 1. Introduction: Chronic Renal Disease - p. 3 3. Part II. Classification and Measurement - p. 6 4. Chapter 2. From Bright's Disease to Chronic Kidney Disease - p. 9 5. Chapter 3. Classification of Chronic Kidney Disease—Historic Perspective: From Insufficiency and Failure to Chronic Kidney Disease - p. 23 6. Chapter 4. Assessing Kidney Function - p. 37 7. Chapter 5. Clinical Assessment and Management of Chronic Kidney Disease Across Its Stages - p. 55 8. Part III. Epidemiology - p. 71 9. Chapter 6. Epidemiology of Chronic Kidney Disease—Scope of the Problem - p. 75 10. Chapter 7. Gender Issues in Chronic Kidney Disease - p. 91 11. Chapter 8. Ethnicity and Chronic Kidney Disease—United States - p. 111 12. Chapter 9. Ethnicity and Chronic Kidney Disease in Disadvantaged Populations—An International Perspective - p. 121 13. Chapter 10. Ethnicity and Chronic Kidney Disease in Japan - p. 139 14. Chapter 11. Ethnicity and Chronic Kidney Disease in Africa - p. 149 15. Chapter 12. Ethnicity and Chronic Kidney Disease in China - p. 167 16. Chapter 13. Poverty and Chronic Kidney Disease - p. 181 17. Part IV. Pathophysiology - p. 196 18. Chapter 14. The Uremic Syndrome - p. 199 19. Chapter 15. Pathophysiology of Proteinuria: Albuminuria as a Target for Treatment - p. 211 20. Chapter 16. Protein Energy Metabolism in Chronic Kidney Disease - p. 225 21. Chapter 17. Aging and the Kidney: Clinical and Pathophysiologic Issues - p. 249 22. Chapter 18. Pathophysiology of Chronic Kidney Disease Progression: Organ and Cellular Considerations - p. 263 23. Chapter 19. Pathophysiology of Diabetic Nephropathy - p. 279 24. Chapter 20. Prenatal Antecedents of Chronic Kidney Disease - p. 297 25. Chapter 21. Pathophysiology of Hypertension in Chronic Kidney Disease - p. 313 26. Chapter 22. Chronic Kidney Disease and the Vascular Endothelium - p. 323 27. Chapter 23. Cardiovascular Disease and Chronic Kidney Disease - p. 337 28. Chapter 24. Inflammation in Chronic Kidney Disease - p. 355 29. Chapter 25. Genetics and Chronic Kidney Disease - p. 375 30. Chapter 26. Acute Kidney Injury and Chronic Kidney Disease - p. 397 31. Part V. Complications of Chronic Kidney Disease - p. 409 32. Chapter 27. Psychosocial Issues in Chronic Kidney Disease Patients - p. 413 33. Chapter 28. Ophthalmic Issues in Chronic Kidney Disease - p. 425 34. Chapter 29. Neurologic Complications of Chronic Kidney Disease - p. 441 35. Chapter 30. Hematologic Complications of Chronic Kidney Disease—Anemia and Platelet Disorders - p. 463 36. Chapter 31. Hematologic and Infectious Complications of Chronic Kidney Disease - p. 477 37. Chapter 32. Immune Function in Chronic Kidney Disease - p. 503 38. Chapter 33. Chronic Kidney Disease and Gastrointestinal Disorders - p. 521 39. Chapter 34. Endocrine Complications of Chronic Kidney Disease - p. 541 40. Chapter 35. Chronic Kidney Disease–Mineral and Bone Disorders - p. 551 41. Chapter 36. Sleep Disorders in Chronic Kidney Disease - p. 571 42. Chapter 37. Sexual Dysfunction in Chronic Kidney Disease - p. 593 43. Part VI. Fluid and Electrolyte Disorders in Chronic Kidney Disease - p. 611 44. Chapter 38. Water Homeostasis in Chronic Kidney Disease - p. 615 45. Chapter 39. Sodium Metabolism in Chronic Kidney Disease - p. 633 46. Chapter 40. Potassium Metabolism in Chronic Kidney Disease - p. 643 47. Chapter 41. Calcium, Phosphate, and Magnesium Metabolism in Chronic Kidney Disease - p. 661 48. Chapter 42. Acid/Base Metabolism in Chronic Kidney Disease - p. 681 49. Chapter 43. Uric Acid Metabolism and the Kidney - p. 689 50. Chapter 44. Trace Elements in Chronic Kidney Disease - p. 703 51. Chapter 45. Approach to the Patient with Chronic Glomerular Disease - p. 721 52. Chapter 46. Approach to the Patient with Hypertensive Nephrosclerosis - p. 737 53. Part VII. Chronic Kidney Disease and Systemic Illnesses - Clinical Considerations - p. 752 54. Chapter 47. Approach to the Patient with Chronic Kidney Disease and Renovascular Disease - p. 753 55. Chapter 48. Polycystic Kidney Disease - p. 771 56. Chapter 49. Lupus Nephritis - p. 799 57. Chapter 50. Sickle Cell Disease - p. 813 58. Chapter 51. Approach to Chronic Kidney Disease in the Diabetic Patient - p. 831 59. Chapter 52. Human Immunodeficiency Virus Infection and Chronic Kidney Disease - p. 849 60. Chapter 53. Liver Disease and Chronic Kidney Disease - p. 863 61. Chapter 54. Chronic Kidney Disease and Heart Failure—A Nephrologic Approach - p. 883 62. Chapter 55. Cancer and Chronic Kidney Disease - p. 899 63. Part VIII. Therapeutic Considerations - p. 917 64. Chapter 56. The Interdisciplinary Clinic for Chronic Kidney Disease - p. 921 65. Chapter 57. Slowing Progression of Chronic Kidney Disease - p. 937 66. Chapter 58. Approach to the Patient with Non-nephrotic Proteinuria - p. 961 67. Chapter 59. Nutritional Management of Patients with Chronic Kidney Disease - p. 975 68. Chapter 60. Management of Anemia in Chronic Kidney Disease - p. 991 69. Chapter 61. Management of Hypertension in Chronic Kidney Disease - p. 1001 70. Chapter 62. Management of Mineral and Bone Disorders in Chronic Kidney Disease - p. 1013 71. Chapter 63. Drug Metabolism in Chronic Kidney Disease - p. 1035 72. Chapter 64. Use of Diuretics in Chronic Kidney Disease Patients - p. 1053 73. Chapter 65. Nonsteroidal Antiinflammatory Drugs and Opioids in Chronic Kidney Disease - p. 1071 74. Chapter 66. Dyslipidemia and Chronic Kidney Disease - p. 1093 75. Chapter 67. Nephrolithiasis, Nephrocalcinosis, and Hypercalciuria - p. 1103 76. Chapter 68. Treatment of Psychiatric Disorders in Chronic Kidney Disease Patients - p. 1123 77. Chapter 69. Preparing for Transplantation - p. 1141 78. Chapter 70. Preparing for Hemodialysis - p. 1157 79. Chapter 71. Preparing for Peritoneal Dialysis - p. 1175 80. Part IX. Special Considerations - p. 1185 81. Chapter 72. Emerging Therapies - p. 1189 82. Chapter 73. The Renal Biopsy in Chronic Kidney Disease - p. 1207 83. Chapter 74. Pregnancy and Kidney Disease - p. 1223 84. Chapter 75. Chronic Kidney Disease in Children - p. 1239 85. Chapter 76. Reflux Nephropathy - p. 1255 86. Chapter 77. Chronic Kidney Disease in the Elderly—Who Has It? Who Does One Treat? and How are They to be Treated? - p. 1265 87. Chapter 78. Pain and Chronic Kidney Disease - p. 1279 88. Chapter 79. The Perioperative Management of the Patient with Chronic Kidney Disease - p. 1291 89. Chapter 80. Ethical Issues in Chronic Kidney Disease Patients - p. 1309 90. Chapter 81. Imaging the Chronic Kidney Disease Patient - p. 1321 91. Index - p. 1333
Chronic Renal Disease, Second Edition, comprehensively investigates the physiology, pathophysiology, treatment and management of chronic kidney disease (CKD). This translational reference takes an in-depth look at CKD with no coverage of dialysis or transplantation. Chapters are devoted to the scientific investigation of chronic kidney disease, the most common problems faced by nephrologists in the management of chronic kidney disease, specific illnesses in the CKD framework, and how the management of CKD in a polycystic kidney disease patient differs from other CKD patients. This award-winning reference features a series of case studies, covering both clinical aspects and pathophysiology.
Questions are open ended, progressively more difficult, and repetitive across different patient clinical problems and different chapters. The cases and questions included will be useful for medical students, residency board reviews, and clinician teaching or conference preparation.
1. Part I. Introduction - p. xxi 2. Chapter 1. Introduction: Chronic Renal Disease - p. 3 3. Part II. Classification and Measurement - p. 6 4. Chapter 2. From Bright's Disease to Chronic Kidney Disease - p. 9 5. Chapter 3. Classification of Chronic Kidney Disease—Historic Perspective: From Insufficiency and Failure to Chronic Kidney Disease - p. 23 6. Chapter 4. Assessing Kidney Function - p. 37 7. Chapter 5. Clinical Assessment and Management of Chronic Kidney Disease Across Its Stages - p. 55 8. Part III. Epidemiology - p. 71 9. Chapter 6. Epidemiology of Chronic Kidney Disease—Scope of the Problem - p. 75 10. Chapter 7. Gender Issues in Chronic Kidney Disease - p. 91 11. Chapter 8. Ethnicity and Chronic Kidney Disease—United States - p. 111 12. Chapter 9. Ethnicity and Chronic Kidney Disease in Disadvantaged Populations—An International Perspective - p. 121 13. Chapter 10. Ethnicity and Chronic Kidney Disease in Japan - p. 139 14. Chapter 11. Ethnicity and Chronic Kidney Disease in Africa - p. 149 15. Chapter 12. Ethnicity and Chronic Kidney Disease in China - p. 167 16. Chapter 13. Poverty and Chronic Kidney Disease - p. 181 17. Part IV. Pathophysiology - p. 196 18. Chapter 14. The Uremic Syndrome - p. 199 19. Chapter 15. Pathophysiology of Proteinuria: Albuminuria as a Target for Treatment - p. 211 20. Chapter 16. Protein Energy Metabolism in Chronic Kidney Disease - p. 225 21. Chapter 17. Aging and the Kidney: Clinical and Pathophysiologic Issues - p. 249 22. Chapter 18. Pathophysiology of Chronic Kidney Disease Progression: Organ and Cellular Considerations - p. 263 23. Chapter 19. Pathophysiology of Diabetic Nephropathy - p. 279 24. Chapter 20. Prenatal Antecedents of Chronic Kidney Disease - p. 297 25. Chapter 21. Pathophysiology of Hypertension in Chronic Kidney Disease - p. 313 26. Chapter 22. Chronic Kidney Disease and the Vascular Endothelium - p. 323 27. Chapter 23. Cardiovascular Disease and Chronic Kidney Disease - p. 337 28. Chapter 24. Inflammation in Chronic Kidney Disease - p. 355 29. Chapter 25. Genetics and Chronic Kidney Disease - p. 375 30. Chapter 26. Acute Kidney Injury and Chronic Kidney Disease - p. 397 31. Part V. Complications of Chronic Kidney Disease - p. 409 32. Chapter 27. Psychosocial Issues in Chronic Kidney Disease Patients - p. 413 33. Chapter 28. Ophthalmic Issues in Chronic Kidney Disease - p. 425 34. Chapter 29. Neurologic Complications of Chronic Kidney Disease - p. 441 35. Chapter 30. Hematologic Complications of Chronic Kidney Disease—Anemia and Platelet Disorders - p. 463 36. Chapter 31. Hematologic and Infectious Complications of Chronic Kidney Disease - p. 477 37. Chapter 32. Immune Function in Chronic Kidney Disease - p. 503 38. Chapter 33. Chronic Kidney Disease and Gastrointestinal Disorders - p. 521 39. Chapter 34. Endocrine Complications of Chronic Kidney Disease - p. 541 40. Chapter 35. Chronic Kidney Disease–Mineral and Bone Disorders - p. 551 41. Chapter 36. Sleep Disorders in Chronic Kidney Disease - p. 571 42. Chapter 37. Sexual Dysfunction in Chronic Kidney Disease - p. 593 43. Part VI. Fluid and Electrolyte Disorders in Chronic Kidney Disease - p. 611 44. Chapter 38. Water Homeostasis in Chronic Kidney Disease - p. 615 45. Chapter 39. Sodium Metabolism in Chronic Kidney Disease - p. 633 46. Chapter 40. Potassium Metabolism in Chronic Kidney Disease - p. 643 47. Chapter 41. Calcium, Phosphate, and Magnesium Metabolism in Chronic Kidney Disease - p. 661 48. Chapter 42. Acid/Base Metabolism in Chronic Kidney Disease - p. 681 49. Chapter 43. Uric Acid Metabolism and the Kidney - p. 689 50. Chapter 44. Trace Elements in Chronic Kidney Disease - p. 703 51. Chapter 45. Approach to the Patient with Chronic Glomerular Disease - p. 721 52. Chapter 46. Approach to the Patient with Hypertensive Nephrosclerosis - p. 737 53. Part VII. Chronic Kidney Disease and Systemic Illnesses - Clinical Considerations - p. 752 54. Chapter 47. Approach to the Patient with Chronic Kidney Disease and Renovascular Disease - p. 753 55. Chapter 48. Polycystic Kidney Disease - p. 771 56. Chapter 49. Lupus Nephritis - p. 799 57. Chapter 50. Sickle Cell Disease - p. 813 58. Chapter 51. Approach to Chronic Kidney Disease in the Diabetic Patient - p. 831 59. Chapter 52. Human Immunodeficiency Virus Infection and Chronic Kidney Disease - p. 849 60. Chapter 53. Liver Disease and Chronic Kidney Disease - p. 863 61. Chapter 54. Chronic Kidney Disease and Heart Failure—A Nephrologic Approach - p. 883 62. Chapter 55. Cancer and Chronic Kidney Disease - p. 899 63. Part VIII. Therapeutic Considerations - p. 917 64. Chapter 56. The Interdisciplinary Clinic for Chronic Kidney Disease - p. 921 65. Chapter 57. Slowing Progression of Chronic Kidney Disease - p. 937 66. Chapter 58. Approach to the Patient with Non-nephrotic Proteinuria - p. 961 67. Chapter 59. Nutritional Management of Patients with Chronic Kidney Disease - p. 975 68. Chapter 60. Management of Anemia in Chronic Kidney Disease - p. 991 69. Chapter 61. Management of Hypertension in Chronic Kidney Disease - p. 1001 70. Chapter 62. Management of Mineral and Bone Disorders in Chronic Kidney Disease - p. 1013 71. Chapter 63. Drug Metabolism in Chronic Kidney Disease - p. 1035 72. Chapter 64. Use of Diuretics in Chronic Kidney Disease Patients - p. 1053 73. Chapter 65. Nonsteroidal Antiinflammatory Drugs and Opioids in Chronic Kidney Disease - p. 1071 74. Chapter 66. Dyslipidemia and Chronic Kidney Disease - p. 1093 75. Chapter 67. Nephrolithiasis, Nephrocalcinosis, and Hypercalciuria - p. 1103 76. Chapter 68. Treatment of Psychiatric Disorders in Chronic Kidney Disease Patients - p. 1123 77. Chapter 69. Preparing for Transplantation - p. 1141 78. Chapter 70. Preparing for Hemodialysis - p. 1157 79. Chapter 71. Preparing for Peritoneal Dialysis - p. 1175 80. Part IX. Special Considerations - p. 1185 81. Chapter 72. Emerging Therapies - p. 1189 82. Chapter 73. The Renal Biopsy in Chronic Kidney Disease - p. 1207 83. Chapter 74. Pregnancy and Kidney Disease - p. 1223 84. Chapter 75. Chronic Kidney Disease in Children - p. 1239 85. Chapter 76. Reflux Nephropathy - p. 1255 86. Chapter 77. Chronic Kidney Disease in the Elderly—Who Has It? Who Does One Treat? and How are They to be Treated? - p. 1265 87. Chapter 78. Pain and Chronic Kidney Disease - p. 1279 88. Chapter 79. The Perioperative Management of the Patient with Chronic Kidney Disease - p. 1291 89. Chapter 80. Ethical Issues in Chronic Kidney Disease Patients - p. 1309 90. Chapter 81. Imaging the Chronic Kidney Disease Patient - p. 1321 91. Index - p. 1333
