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This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Historical Perspective on the Current Renaissance for Hematopoietic Stem Cell Gene Therapy - p. 721 9. Integrating Vectors for Gene Therapy and Clonal Tracking of Engineered Hematopoiesis - p. 737 10. Nonintegrating Gene Therapy Vectors - p. 753 11. In Vivo Hematopoietic Stem Cell Transduction - p. 771 12. Therapeutic Gene Editing Safety and Specificity - p. 787 13. Gene Editing: Regulatory and Translation to Clinic - p. 797 14. Opening Marrow Niches in Patients Undergoing Autologous Hematopoietic Stem Cell Gene Therapy - p. 809 15. Gene Therapy Approaches to Immunodeficiency - p. 823 16. Gene Therapy Approaches to Hemoglobinopathies - p. 835 17. Gene Therapy for Hemophilia - p. 853 18. Hematopoietic Gene Therapies for Metabolic and Neurologic Diseases - p. 869 19. Gene Therapy Approaches to Human Immunodeficiency Virus and Other Infectious Diseases - p. 883 20. Hematopoietic Stem Cell Approaches to Cancer - p. 897 21. Gene Modified T Cell Therapies for Hematological Malignancies - p. 913

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This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Historical Perspective on the Current Renaissance for Hematopoietic Stem Cell Gene Therapy - p. 721 9. Integrating Vectors for Gene Therapy and Clonal Tracking of Engineered Hematopoiesis - p. 737 10. Nonintegrating Gene Therapy Vectors - p. 753 11. In Vivo Hematopoietic Stem Cell Transduction - p. 771 12. Therapeutic Gene Editing Safety and Specificity - p. 787 13. Gene Editing: Regulatory and Translation to Clinic - p. 797 14. Opening Marrow Niches in Patients Undergoing Autologous Hematopoietic Stem Cell Gene Therapy - p. 809 15. Gene Therapy Approaches to Immunodeficiency - p. 823 16. Gene Therapy Approaches to Hemoglobinopathies - p. 835 17. Gene Therapy for Hemophilia - p. 853 18. Hematopoietic Gene Therapies for Metabolic and Neurologic Diseases - p. 869 19. Gene Therapy Approaches to Human Immunodeficiency Virus and Other Infectious Diseases - p. 883 20. Hematopoietic Stem Cell Approaches to Cancer - p. 897 21. Gene Modified T Cell Therapies for Hematological Malignancies - p. 913

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