Ideal for neurologists and other health care professionals who treat patients with neuromuscular diseases, Neuromuscular Case Studies, 2nd Edition, presents more than 100 cases of both common and rare neuromuscular disorders. Dr. Tulio E. Bertorini provides the latest tools and strategies for diagnosis and management that minimize disability and maximize quality of life for your patients, including up-to-date coverage of numerous recent advances in the field. Using a multidisciplinary approach, this practical text contains two parts: the first includes basic aspects of anatomy, physiology, diagnostic tests, and therapeutic strategies; the second describes specific cases and their diagnosis and management.
Presents a multidisciplinary approach to the management and therapeutic treatment of the full range of neuromuscular disorders and resulting complications.
Covers the latest advances in the field, including genetic causes of hereditary diseases, new autoimmune diseases, and promising new therapies such as antisense oligonucleotides, gene therapies, and immunotherapy.
Includes the wide range of disorders that fall under each disease classification (e.g., the Motor Neuron Diseases chapter includes all forms of spinal atrophy, ALS, neuropathies and myopathies, as well as disorders of neuromuscular transmission). In turn, each disease section includes diagnosis and evaluation, treatment, outcome, and suggested readings.
Uses a reader-friendly format that takes you step by step through the diagnosis and treatment of neuromuscular disorders, from the basic anatomy and physiology of the nerve and muscle through to clinical evaluation, diagnostic testing, and therapy.
Reviews the etiologies, pathogenesis, differential diagnosis, and management of each disorder, helping you not only recognize its presentation, but also determine the best treatment plan.
Arranges case studies and indexes both by complaint and by diagnosis.
Features full-color clinical images and diagrams — along with numerous diagnosis tools, tables and treatment algorithms throughout — that make complex concepts easier to understand and apply.
Shares the knowledge and experience of an expert in clinical neuromuscular care.
1. Introduction - p. vii 2. Chapter 1: Neuromuscular Anatomy and Function - p. vii 3. Chapter 2: Neurologic Evaluation and Ancillary Tests - p. 24 4. Chapter 3: Therapy in Neuromuscular Diseases - p. 70 5. Case Studies - p. 89 6. Chapter 4: An Elderly Woman With Numbness in the Hands - p. 89 7. Chapter 5: A Diabetic Man With Arm Swelling, Pain, and Numbness - p. 97 8. Chapter 6: A Diabetic Man With Hand Numbness and Fainting Spells - p. 102 9. Chapter 7: A Man With Hand Pain - p. 108 10. Chapter 8: A Woman With Hand Weakness, Numbness, and Pain After Cardiac Catheterization - p. 112 11. Chapter 9: A Man Who Practices Karate and Has Forearm Pain - p. 115 12. Chapter 10: A Man With a History of Polio Who Developed Hand Weakness and Numbness - p. 118 13. Chapter 11: A Young Woman With Multiple Sclerosis and Hand Numbness - p. 124 14. Chapter 12: A Woman With a Wrist Drop and a Mass in the Arm - p. 129 15. Chapter 13: A Man With Bilateral Arm Weakness After Lumbar Surgery - p. 133 16. Chapter 14: A Woman With Acute Onset of Shoulder Pain and Weakness - p. 138 17. Chapter 15: A Man With Lymphoma and Numbness in the Fingers of One Hand - p. 143 18. Chapter 16: A Woman With Arm Weakness After Treatment for Breast Cancer - p. 146 19. Chapter 17: A Diabetic Man With Shoulder Pain and Weakness - p. 150 20. Chapter 18: A Woman With Arm Weakness and a Skin Rash - p. 153 21. Chapter 19: A Woman With Neck and Arm Pain - p. 157 22. Chapter 20: A Woman With Neck Pain and a Weak Arm - p. 159 23. Chapter 21: A Woman With Back Pain and Leg Weakness - p. 163 24. Chapter 22: A Woman With Back Pain and Weakness - p. 167 25. Chapter 23: A Woman With Back Pain and Unusual Nerve Conduction Tests - p. 169 26. Chapter 24: A Man With Pheochromocytoma and Back Pain - p. 173 27. Chapter 25: A Diabetic Man With Back and Leg Pain - p. 177 28. Chapter 26: A Man With Leg Pain While Walking - p. 180 29. Chapter 27: A Man With Foot Pain - p. 184 30. Chapter 28: A Man With Unilateral Proximal Leg Weakness After Heart Catheterization - p. 188 31. Chapter 29: A Woman With Uterine Cancer and Unilateral Leg Weakness - p. 191 32. Chapter 30: A Man With Burning Sensations in the Thigh - p. 196 33. Chapter 31: A Man With Weakness and Fasciculations in the Lower Extremities - p. 199 34. Chapter 32: A Woman With Unilateral Facial Weakness - p. 202 35. Chapter 33: A Diabetic Woman With Muscle Weakness and Ophthalmoplegia - p. 205 36. Chapter 34: A Man With a Dropped Head - p. 210 37. Chapter 35: A Man in the “Barrel” - p. 217 38. Chapter 36: A Man With a Long History of Muscle Weakness in One Arm - p. 222 39. Chapter 37: A Young Man With Longstanding Weakness in Both Arms - p. 225 40. Chapter 38: A Man With Progressive Leg Muscle Weakness 20 Years After an Acute Paralysis - p. 228 41. Chapter 39: A Man With One Large Calf - p. 233 42. Chapter 40: A Man With Muscle Spasms and Elevated Serum Creatine Kinase - p. 237 43. Chapter 41: A Man With Muscle Twitching and Poor Balance - p. 243 44. Chapter 42: A Floppy Child - p. 248 45. Chapter 43: A Man With Acute Areflexic Paralysis and Central Nervous System Symptoms - p. 255 46. Chapter 44: A Man With Acute Muscle Weakness and Respiratory Failure - p. 261 47. Chapter 45: A Young Woman With Acute Onset of Clumsiness and Ophthalmoplegia - p. 266 48. Chapter 46: A Woman With Seafood Poisoning in Catfish Country - p. 270 49. Chapter 47: A Woman With a Kingly Disease - p. 274 50. Chapter 48: A Myasthenic Woman With Persistent Weakness - p. 281 51. Chapter 49: A Woman With COVID-19 Infection and Quadriparesis - p. 287 52. Chapter 50: A Man With Neck Pain and Numbness in the Hands - p. 290 53. Chapter 51: A Woman With Peripheral Neuropathy and Frequent Falls - p. 292 54. Chapter 52: A Woman With Progressive Four Limb Paresthesias - p. 296 55. Chapter 53: An Elderly Woman With Frequent Falls and Abnormal MRI - p. 300 56. Chapter 54: A Man With Weakness in the Legs - p. 302 57. Chapter 55: An Elderly Woman With Asymmetric Weakness and a Monoclonal Gammopathy - p. 305 58. Chapter 56: A Man With Progressive Weakness and Fasciculations - p. 308 59. Chapter 57: A Man With Diabetic Polyneuropathy Who Developed Rapidly Progressive Weakness - p. 317 60. Chapter 58: An Older Man With Leg Numbness - p. 324 61. Chapter 59: An Elderly Man With a Peripheral Neuropathy Like His Sister - p. 328 62. Chapter 60: A Man With Progressive Lower Extremity Weakness and Monoclonal Gammopathy - p. 331 63. Chapter 61: A Woman With a Neuropathy and Symptoms of a Central Nervous System Disease - p. 337 64. Chapter 62: A Man With Progressive Weakness After a Gastroplasty - p. 343 65. Chapter 63: A Diabetic Woman With Unilateral Proximal Leg Weakness and Pain - p. 347 66. Chapter 64: A Diabetic Man With Bilateral Arm Weakness - p. 350 67. Chapter 65: A Diabetic Man With Acute Onset of Pain and Swelling in the Thigh - p. 355 68. Chapter 66: A Uremic Man With Burning Feet - p. 357 69. Chapter 67: A Woman With Leg Numbness, Pain, Weakness, and Slow Nerve Conduction Velocities - p. 360 70. Chapter 68: A Boy With Leg Weakness - p. 364 71. Chapter 69: A Man With Hand Weakness and Numbness After Skiing - p. 372 72. Chapter 70: A Man With Recurrent Foot Drop - p. 375 73. Chapter 71: An Elderly Woman With Foot Drop and Hand Weakness - p. 380 74. Chapter 72: A Woman With Rheumatoid Arthritis Who Developed Numbness and Pain in the Feet - p. 386 75. Chapter 73: A Woman With Granulomatous Lesions in the Lungs and a Peripheral Neuropathy - p. 390 76. Chapter 74: A Man With a Neuropathy, Weight Loss, and Lung Nodules - p. 395 77. Chapter 75: A Woman With Difficulty Walking and Ataxia - p. 399 78. Chapter 76: A Man With Progressive Neuropathy and Congestive Heart Failure - p. 406 79. Chapter 77: A Woman With a Demyelinating and Axonal Neuropathy - p. 411 80. Chapter 78: An Elderly Woman With a Progressive Neuropathy - p. 413 81. Chapter 79: A Young Woman With Difficulty Swallowing - p. 417 82. Chapter 80: A Young Woman With Intermittent Weakness and a Positive Family History of Similar Problems - p. 420 83. Chapter 81: A Weak Woman With a Weak Baby - p. 425 84. Chapter 82: A Woman With Muscle Weakness and Areflexia - p. 429 85. Chapter 83: An Elderly Woman With Proximal Weakness - p. 432 86. Chapter 84: An Elderly Woman With Ptosis, Areflexia, and Weakness - p. 437 87. Chapter 85: A Young Woman With Distal Upper Extremity Weakness - p. 439 88. Chapter 86: A Young Man With Episodic Weakness - p. 449 89. Chapter 87: An African American Man With Hyperthyroidism and Acute Paralysis - p. 454 90. Chapter 88: A Boy With Large Muscles, Leg Pain, and Elevated Serum Creatine Kinase - p. 455 91. Chapter 89: A Woman With Proximal Muscle Weakness, Calf Hypertrophy, Heel Contractures, and Elevated Serum Creatine Kinase - p. 463 92. Chapter 90: A Young Man With Distal Leg Wasting and Normal Sensation - p. 467 93. Chapter 91: A Boy With Proximal Weakness and Cardiomyopathy - p. 475 94. Chapter 92: A Woman With Droopy Eyelids and Difficulty Swallowing - p. 481 95. Chapter 93: A Man With Facial and Shoulder Muscle Weakness - p. 485 96. Chapter 94: A Boy Born Floppy With Severe Weakness and, Later, Contractures - p. 489 97. Chapter 95: A Woman With Long-standing Weakness and Foot Deformities - p. 496 98. Chapter 96: A floppy baby who later developed malignant hyperthermia - p. 501 99. Chapter 97: A Woman With Droopy Eyelids and Ophthalmoplegia - p. 505 100. Chapter 98: A Man With Weakness and Swelling in the Neck - p. 512 101. Chapter 99: A Woman With Muscle Pains and Dark Urine - p. 515 102. Chapter 100: A Woman With Progressive Proximal Muscle Weakness - p. 521 103. Chapter 101: A Sedentary Man With Acute Respiratory Failure and Myoglobinuria - p. 527 104. Chapter 102: An Elderly Man With New Onset Weakness - p. 533 105. Chapter 103: A Uremic Man With Proximal Muscle Weakness - p. 537 106. Chapter 104: A Woman With Weakness, Elevated Cholesterol, and Serum Creatine Kinase Levels - p. 541 107. Chapter 105: An Older Woman With Leg Weakness and Atrophic Muscle Fibers on Biopsy - p. 544 108. Chapter 106: A Woman With Muscle Weakness and a Skin Rash - p. 548 109. Chapter 107: A Child With Muscle Weakness and a Skin Rash - p. 552 110. Chapter 108: A Man With Muscle Pains - p. 556 111. Chapter 109: An Older Woman With Progressive Muscle Weakness - p. 561 112. Chapter 110: An Elderly Man With Weakness Diagnosed as Having a Myopathy and a Neuropathy - p. 565 113. Chapter 111: An HIV-Infected Man With Muscle Weakness and Spasms - p. 569 114. Chapter 112: A Patient With Rapidly Progressive Muscle Weakness and Rather Elevated Creatine Kinase - p. 573 115. Chapter 113: A Woman With Painful and Swollen Legs - p. 575 116. Chapter 114: A Man With a Bent Spine - p. 579 117. Chapter 115: A Man With Muscle Stiffness and Later With Diplopia - p. 582 118. Chapter 116: A Woman With Muscle Cramps and Fasciculations - p. 589 119. Chapter 117: A Young Man With Large and Stiff Muscles - p. 595 120. Chapter 118: A Woman With Generalized Increased Insertional Activity on EMG - p. 601 121. Chapter 119: A Boy With Short Stature, Small Jaw, Muscle Hypertrophy, and Stiffness - p. 604 122. Chapter 120: An Elderly Woman With Muscle Spasms - p. 607 123. Chapter 121: A Woman With Proximal Muscle Weakness and Neuromuscular Irritability - p. 610 124. Chapter 122: A Woman With Focal Spontaneous Muscle Movements - p. 613 125. Index of Cases by Diagnosis - p. 617 126. Index - p. 617 127. Confidence is ClinicalKey - p. 617
Ideal for neurologists and other health care professionals who treat patients with neuromuscular diseases, Neuromuscular Case Studies, 2nd Edition, presents more than 100 cases of both common and rare neuromuscular disorders. Dr. Tulio E. Bertorini provides the latest tools and strategies for diagnosis and management that minimize disability and maximize quality of life for your patients, including up-to-date coverage of numerous recent advances in the field. Using a multidisciplinary approach, this practical text contains two parts: the first includes basic aspects of anatomy, physiology, diagnostic tests, and therapeutic strategies; the second describes specific cases and their diagnosis and management.
Presents a multidisciplinary approach to the management and therapeutic treatment of the full range of neuromuscular disorders and resulting complications.
Covers the latest advances in the field, including genetic causes of hereditary diseases, new autoimmune diseases, and promising new therapies such as antisense oligonucleotides, gene therapies, and immunotherapy.
Includes the wide range of disorders that fall under each disease classification (e.g., the Motor Neuron Diseases chapter includes all forms of spinal atrophy, ALS, neuropathies and myopathies, as well as disorders of neuromuscular transmission). In turn, each disease section includes diagnosis and evaluation, treatment, outcome, and suggested readings.
Uses a reader-friendly format that takes you step by step through the diagnosis and treatment of neuromuscular disorders, from the basic anatomy and physiology of the nerve and muscle through to clinical evaluation, diagnostic testing, and therapy.
Reviews the etiologies, pathogenesis, differential diagnosis, and management of each disorder, helping you not only recognize its presentation, but also determine the best treatment plan.
Arranges case studies and indexes both by complaint and by diagnosis.
Features full-color clinical images and diagrams — along with numerous diagnosis tools, tables and treatment algorithms throughout — that make complex concepts easier to understand and apply.
Shares the knowledge and experience of an expert in clinical neuromuscular care.
1. Introduction - p. vii 2. Chapter 1: Neuromuscular Anatomy and Function - p. vii 3. Chapter 2: Neurologic Evaluation and Ancillary Tests - p. 24 4. Chapter 3: Therapy in Neuromuscular Diseases - p. 70 5. Case Studies - p. 89 6. Chapter 4: An Elderly Woman With Numbness in the Hands - p. 89 7. Chapter 5: A Diabetic Man With Arm Swelling, Pain, and Numbness - p. 97 8. Chapter 6: A Diabetic Man With Hand Numbness and Fainting Spells - p. 102 9. Chapter 7: A Man With Hand Pain - p. 108 10. Chapter 8: A Woman With Hand Weakness, Numbness, and Pain After Cardiac Catheterization - p. 112 11. Chapter 9: A Man Who Practices Karate and Has Forearm Pain - p. 115 12. Chapter 10: A Man With a History of Polio Who Developed Hand Weakness and Numbness - p. 118 13. Chapter 11: A Young Woman With Multiple Sclerosis and Hand Numbness - p. 124 14. Chapter 12: A Woman With a Wrist Drop and a Mass in the Arm - p. 129 15. Chapter 13: A Man With Bilateral Arm Weakness After Lumbar Surgery - p. 133 16. Chapter 14: A Woman With Acute Onset of Shoulder Pain and Weakness - p. 138 17. Chapter 15: A Man With Lymphoma and Numbness in the Fingers of One Hand - p. 143 18. Chapter 16: A Woman With Arm Weakness After Treatment for Breast Cancer - p. 146 19. Chapter 17: A Diabetic Man With Shoulder Pain and Weakness - p. 150 20. Chapter 18: A Woman With Arm Weakness and a Skin Rash - p. 153 21. Chapter 19: A Woman With Neck and Arm Pain - p. 157 22. Chapter 20: A Woman With Neck Pain and a Weak Arm - p. 159 23. Chapter 21: A Woman With Back Pain and Leg Weakness - p. 163 24. Chapter 22: A Woman With Back Pain and Weakness - p. 167 25. Chapter 23: A Woman With Back Pain and Unusual Nerve Conduction Tests - p. 169 26. Chapter 24: A Man With Pheochromocytoma and Back Pain - p. 173 27. Chapter 25: A Diabetic Man With Back and Leg Pain - p. 177 28. Chapter 26: A Man With Leg Pain While Walking - p. 180 29. Chapter 27: A Man With Foot Pain - p. 184 30. Chapter 28: A Man With Unilateral Proximal Leg Weakness After Heart Catheterization - p. 188 31. Chapter 29: A Woman With Uterine Cancer and Unilateral Leg Weakness - p. 191 32. Chapter 30: A Man With Burning Sensations in the Thigh - p. 196 33. Chapter 31: A Man With Weakness and Fasciculations in the Lower Extremities - p. 199 34. Chapter 32: A Woman With Unilateral Facial Weakness - p. 202 35. Chapter 33: A Diabetic Woman With Muscle Weakness and Ophthalmoplegia - p. 205 36. Chapter 34: A Man With a Dropped Head - p. 210 37. Chapter 35: A Man in the “Barrel” - p. 217 38. Chapter 36: A Man With a Long History of Muscle Weakness in One Arm - p. 222 39. Chapter 37: A Young Man With Longstanding Weakness in Both Arms - p. 225 40. Chapter 38: A Man With Progressive Leg Muscle Weakness 20 Years After an Acute Paralysis - p. 228 41. Chapter 39: A Man With One Large Calf - p. 233 42. Chapter 40: A Man With Muscle Spasms and Elevated Serum Creatine Kinase - p. 237 43. Chapter 41: A Man With Muscle Twitching and Poor Balance - p. 243 44. Chapter 42: A Floppy Child - p. 248 45. Chapter 43: A Man With Acute Areflexic Paralysis and Central Nervous System Symptoms - p. 255 46. Chapter 44: A Man With Acute Muscle Weakness and Respiratory Failure - p. 261 47. Chapter 45: A Young Woman With Acute Onset of Clumsiness and Ophthalmoplegia - p. 266 48. Chapter 46: A Woman With Seafood Poisoning in Catfish Country - p. 270 49. Chapter 47: A Woman With a Kingly Disease - p. 274 50. Chapter 48: A Myasthenic Woman With Persistent Weakness - p. 281 51. Chapter 49: A Woman With COVID-19 Infection and Quadriparesis - p. 287 52. Chapter 50: A Man With Neck Pain and Numbness in the Hands - p. 290 53. Chapter 51: A Woman With Peripheral Neuropathy and Frequent Falls - p. 292 54. Chapter 52: A Woman With Progressive Four Limb Paresthesias - p. 296 55. Chapter 53: An Elderly Woman With Frequent Falls and Abnormal MRI - p. 300 56. Chapter 54: A Man With Weakness in the Legs - p. 302 57. Chapter 55: An Elderly Woman With Asymmetric Weakness and a Monoclonal Gammopathy - p. 305 58. Chapter 56: A Man With Progressive Weakness and Fasciculations - p. 308 59. Chapter 57: A Man With Diabetic Polyneuropathy Who Developed Rapidly Progressive Weakness - p. 317 60. Chapter 58: An Older Man With Leg Numbness - p. 324 61. Chapter 59: An Elderly Man With a Peripheral Neuropathy Like His Sister - p. 328 62. Chapter 60: A Man With Progressive Lower Extremity Weakness and Monoclonal Gammopathy - p. 331 63. Chapter 61: A Woman With a Neuropathy and Symptoms of a Central Nervous System Disease - p. 337 64. Chapter 62: A Man With Progressive Weakness After a Gastroplasty - p. 343 65. Chapter 63: A Diabetic Woman With Unilateral Proximal Leg Weakness and Pain - p. 347 66. Chapter 64: A Diabetic Man With Bilateral Arm Weakness - p. 350 67. Chapter 65: A Diabetic Man With Acute Onset of Pain and Swelling in the Thigh - p. 355 68. Chapter 66: A Uremic Man With Burning Feet - p. 357 69. Chapter 67: A Woman With Leg Numbness, Pain, Weakness, and Slow Nerve Conduction Velocities - p. 360 70. Chapter 68: A Boy With Leg Weakness - p. 364 71. Chapter 69: A Man With Hand Weakness and Numbness After Skiing - p. 372 72. Chapter 70: A Man With Recurrent Foot Drop - p. 375 73. Chapter 71: An Elderly Woman With Foot Drop and Hand Weakness - p. 380 74. Chapter 72: A Woman With Rheumatoid Arthritis Who Developed Numbness and Pain in the Feet - p. 386 75. Chapter 73: A Woman With Granulomatous Lesions in the Lungs and a Peripheral Neuropathy - p. 390 76. Chapter 74: A Man With a Neuropathy, Weight Loss, and Lung Nodules - p. 395 77. Chapter 75: A Woman With Difficulty Walking and Ataxia - p. 399 78. Chapter 76: A Man With Progressive Neuropathy and Congestive Heart Failure - p. 406 79. Chapter 77: A Woman With a Demyelinating and Axonal Neuropathy - p. 411 80. Chapter 78: An Elderly Woman With a Progressive Neuropathy - p. 413 81. Chapter 79: A Young Woman With Difficulty Swallowing - p. 417 82. Chapter 80: A Young Woman With Intermittent Weakness and a Positive Family History of Similar Problems - p. 420 83. Chapter 81: A Weak Woman With a Weak Baby - p. 425 84. Chapter 82: A Woman With Muscle Weakness and Areflexia - p. 429 85. Chapter 83: An Elderly Woman With Proximal Weakness - p. 432 86. Chapter 84: An Elderly Woman With Ptosis, Areflexia, and Weakness - p. 437 87. Chapter 85: A Young Woman With Distal Upper Extremity Weakness - p. 439 88. Chapter 86: A Young Man With Episodic Weakness - p. 449 89. Chapter 87: An African American Man With Hyperthyroidism and Acute Paralysis - p. 454 90. Chapter 88: A Boy With Large Muscles, Leg Pain, and Elevated Serum Creatine Kinase - p. 455 91. Chapter 89: A Woman With Proximal Muscle Weakness, Calf Hypertrophy, Heel Contractures, and Elevated Serum Creatine Kinase - p. 463 92. Chapter 90: A Young Man With Distal Leg Wasting and Normal Sensation - p. 467 93. Chapter 91: A Boy With Proximal Weakness and Cardiomyopathy - p. 475 94. Chapter 92: A Woman With Droopy Eyelids and Difficulty Swallowing - p. 481 95. Chapter 93: A Man With Facial and Shoulder Muscle Weakness - p. 485 96. Chapter 94: A Boy Born Floppy With Severe Weakness and, Later, Contractures - p. 489 97. Chapter 95: A Woman With Long-standing Weakness and Foot Deformities - p. 496 98. Chapter 96: A floppy baby who later developed malignant hyperthermia - p. 501 99. Chapter 97: A Woman With Droopy Eyelids and Ophthalmoplegia - p. 505 100. Chapter 98: A Man With Weakness and Swelling in the Neck - p. 512 101. Chapter 99: A Woman With Muscle Pains and Dark Urine - p. 515 102. Chapter 100: A Woman With Progressive Proximal Muscle Weakness - p. 521 103. Chapter 101: A Sedentary Man With Acute Respiratory Failure and Myoglobinuria - p. 527 104. Chapter 102: An Elderly Man With New Onset Weakness - p. 533 105. Chapter 103: A Uremic Man With Proximal Muscle Weakness - p. 537 106. Chapter 104: A Woman With Weakness, Elevated Cholesterol, and Serum Creatine Kinase Levels - p. 541 107. Chapter 105: An Older Woman With Leg Weakness and Atrophic Muscle Fibers on Biopsy - p. 544 108. Chapter 106: A Woman With Muscle Weakness and a Skin Rash - p. 548 109. Chapter 107: A Child With Muscle Weakness and a Skin Rash - p. 552 110. Chapter 108: A Man With Muscle Pains - p. 556 111. Chapter 109: An Older Woman With Progressive Muscle Weakness - p. 561 112. Chapter 110: An Elderly Man With Weakness Diagnosed as Having a Myopathy and a Neuropathy - p. 565 113. Chapter 111: An HIV-Infected Man With Muscle Weakness and Spasms - p. 569 114. Chapter 112: A Patient With Rapidly Progressive Muscle Weakness and Rather Elevated Creatine Kinase - p. 573 115. Chapter 113: A Woman With Painful and Swollen Legs - p. 575 116. Chapter 114: A Man With a Bent Spine - p. 579 117. Chapter 115: A Man With Muscle Stiffness and Later With Diplopia - p. 582 118. Chapter 116: A Woman With Muscle Cramps and Fasciculations - p. 589 119. Chapter 117: A Young Man With Large and Stiff Muscles - p. 595 120. Chapter 118: A Woman With Generalized Increased Insertional Activity on EMG - p. 601 121. Chapter 119: A Boy With Short Stature, Small Jaw, Muscle Hypertrophy, and Stiffness - p. 604 122. Chapter 120: An Elderly Woman With Muscle Spasms - p. 607 123. Chapter 121: A Woman With Proximal Muscle Weakness and Neuromuscular Irritability - p. 610 124. Chapter 122: A Woman With Focal Spontaneous Muscle Movements - p. 613 125. Index of Cases by Diagnosis - p. 617 126. Index - p. 617 127. Confidence is ClinicalKey - p. 617