The new edition of this landmark text continues to be the ‘one stop reference’ to pharmacology for Australian and New Zealand health science students. Chapters have been thoroughly updated and revised to include the latest information on the clinical use of drugs and their application to specific disciplines within the health professions is highlighted. Organised by body system, it retains the features that have proved popular with students and lecturers, such as Clinical Interest Boxes, Drug Monographs, chapter summaries and review exercises. The text gives a comprehensive introduction to important pharmacology principles and concepts and has a strong focus on therapeutics. Written specifically for the Australasian region, it reflects local generic drug names, availability and clinical uses, along with local aspects of scheduling, drug legislation and ethical issues.
1. UNIT 1 Introduction to Pharmacology - p. xxiv 2. Chapter 1 DRUGS AND MEDICINES - p. 1 3. Chapter 2 PHARMACOTHERAPY: CLINICAL USE OF DRUGS - p. 31 4. Chapter 3 OVER-THE-COUNTER DRUGS AND COMPLEMENTARY THERAPIES - p. 62 5. Chapter 4 LEGAL AND ETHICAL FOUNDATIONS OF PHARMACOTHERAPY - p. 92 6. UNIT 2 Principles of Pharmacology - p. 125 7. Chapter 5 MOLECULAR ASPECTS OF DRUG ACTION AND PHARMACODYNAMICS - p. 126 8. Chapter 6 DRUG ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION - p. 141 9. Chapter 7 PHARMACOGENETICS - p. 162 10. Chapter 8 PHARMACOKINETICS AND DOSING REGIMENS - p. 175 11. Chapter 9 INDIVIDUAL AND LIFESPAN ASPECTS OF DRUG THERAPY - p. 188 12. Chapter 10 ADVERSE DRUG REACTIONS AND DRUG INTERACTIONS - p. 203 13. Unit 3 Drugs Affecting the Peripheral Nervous System - p. 215 14. Chapter 11 OVERVIEW OF THE AUTONOMIC NERVOUS SYSTEM AND DRUGS AFFECTING CHOLINERGIC TRANSMISSION - p. 216 15. Chapter 12 OVERVIEW OF THE SYMPATHETIC NERVOUS SYSTEM AND DRUGS AFFECTING NORADRENERGIC TRANSMISSION - p. 234 16. Chapter 13 OVERVIEW OF THE SOMATIC NERVOUS SYSTEM AND DRUGS AFFECTING NEUROMUSCULAR TRANSMISSION - p. 253 17. Unit 4 Drugs Affecting the Central Nervous System - p. 265 18. Chapter 14 CENTRAL NERVOUS SYSTEM OVERVIEW AND ANAESTHETICS - p. 266 19. Chapter 15 ANALGESICS - p. 308 20. Chapter 16 ANTIANXIETY, SEDATIVE AND HYPNOTIC DRUGS - p. 340 21. Chapter 17 ANTIEPILEPTIC DRUGS - p. 356 22. Chapter 18 PSYCHOTROPIC AGENTS - p. 374 23. Chapter 19 CENTRAL NERVOUS SYSTEM STIMULANTS - p. 405 24. Chapter 20 DRUGS FOR NEURODEGENERATIVE DISORDERS AND HEADACHE - p. 416 25. Chapter 21 DRUG DEPENDENCE AND SOCIAL PHARMACOLOGY - p. 440 26. UNIT 5 Drugs Affecting the Heart and Vascular System - p. 483 27. Chapter 22 OVERVIEW OF THE HEART AND DRUGS AFFECTING CARDIAC FUNCTION - p. 484 28. Chapter 23 DRUGS AFFECTING VASCULAR SMOOTH MUSCLE - p. 512 29. Chapter 24 LIPID-LOWERING DRUGS - p. 536 30. UNIT 6 Drugs Affecting the Urinary System - p. 550 31. Chapter 25 DRUGS AFFECTING THE KIDNEY AND BLADDER - p. 551 32. UNIT 7 Drugs Affecting the Blood - p. 571 33. Chapter 26 DRUGS AFFECTING THROMBOSIS AND HAEMOSTASIS - p. 572 34. Chapter 27 DRUGS AFFECTING THE HAEMOPOIETIC SYSTEM - p. 592 35. UNIT 8 Drugs Affecting the Respiratory System - p. 599 36. Chapter 28 DRUGS USED IN RESPIRATORY DISORDERS - p. 600 37. UNIT 9 Drugs Affecting the Gastrointestinal System - p. 635 38. Chapter 29 DRUGS AFFECTING THE UPPER GASTROINTESTINAL TRACT - p. 636 39. Chapter 30 DRUGS AFFECTING THE LOWER GASTROINTESTINAL TRACT - p. 658 40. UNIT 10 Drugs Affecting the Eye, Ear and Special Senses - p. 669 41. Chapter 31 DRUGS AFFECTING THE EYE - p. 670 42. Chapter 32 DRUGS AFFECTING HEARING, TASTE AND SMELL - p. 697 43. UNIT 11 Drugs Affecting the Endocrine System - p. 708 44. Chapter 33 THE NEUROENDOCRINE SYSTEM AND PITUITARY GLAND - p. 709 45. Chapter 34 THE THYROID GLAND AND ANTITHYROID DRUGS - p. 727 46. Chapter 35 PHARMACOLOGY OF THE ADRENAL CORTEX - p. 741 47. Chapter 36 THE ENDOCRINE PANCREAS AND MANAGEMENT OF DIABETES MELLITUS - p. 756 48. Chapter 37 PHARMACOLOGY OF THE PARATHYROID GLANDS AND BONE - p. 780 49. UNIT 12 Drugs Affecting the Reproductive Systems - p. 796 50. Chapter 38 DRUGS AFFECTING THE FEMALE REPRODUCTIVE SYSTEM - p. 797 51. Chapter 39 DRUGS AFFECTING THE MALE REPRODUCTIVE SYSTEM - p. 823 52. Chapter 40 DRUGS AFFECTING FERTILITY OR SEXUAL FUNCTIONING - p. 833 53. UNIT 13 Drugs Used in Neoplastic Diseases - p. 856 54. Chapter 41 NEOPLASIA AND TREATMENT OF CANCERS - p. 857 55. Chapter 42 ANTINEOPLASTIC AGENTS AND ADJUNCTS - p. 880 56. UNIT 14 Drugs Affecting Microorganisms - p. 912 57. Chapter 43 OVERVIEW OF ANTIMICROBIAL CHEMOTHERAPY AND ANTIBIOTIC RESISTANCE - p. 913 58. Chapter 44 ANTIBACTERIAL DRUGS - p. 925 59. Chapter 45 ANTIFUNGAL AND ANTIVIRAL DRUGS - p. 946 60. Chapter 46 ANTIPROTOZOAL, ANTIMYCOBACTERIAL AND ANTHELMINTIC DRUGS - p. 968 61. UNIT 15 Drugs Affecting Body Defences - p. 988 62. Chapter 47 ANTI-INFLAMMATORY AND IMMUNOMODULATING DRUGS - p. 989 63. Chapter 48 DRUGS AFFECTING THE SKIN - p. 1021 64. UNIT 16 Special Topics - p. 1052 65. Chapter 49 DRUGS IN SPORT - p. 1053 66. Chapter 50 DRUGS IN OBESITY - p. 1072 67. Chapter 51 ENVENOMATION AND ANTIVENOMS - p. 1081 68. Appendixes - p. 1091 69. Appendix 1 ABBREVIATIONS - p. 1092 70. Appendix 2 ANTISEPTICS AND DISINFECTANTS - p. 1097 71. Appendix 3 HERB–, NUTRIENT– AND FOOD–DRUG INTERACTIONS - p. 1098 72. Appendix 4 GLOSSARY - p. 1100 73. Appendix 5 AUSTRALIAN POISONS STANDARD 2013 - p. 1107 74. Appendix 6 THE WORLD HEALTH ORGANIZATION MODEL LIST OF ESSENTIAL MEDICINES - p. 1109 75. FIGURE, TABLE AND PICTURE CREDITS - p. 1113 76. INDEX - p. 1114 77. INDEX - p. 1115 78. A - p. 1115 79. B - p. 1119 80. C - p. 1120 81. D - p. 1123 82. E - p. 1125 83. F - p. 1126 84. G - p. 1126 85. H - p. 1127 86. I - p. 1128 87. J - p. 1130 88. K - p. 1130 89. L - p. 1130 90. M - p. 1131 91. N - p. 1132 92. O - p. 1133 93. P - p. 1134 94. Q - p. 1137 95. R - p. 1137 96. S - p. 1138 97. T - p. 1140 98. U - p. 1141 99. V - p. 1142 100. W - p. 1142 101. X - p. 1142 102. Y - p. 1142 103. Z - p. 1142
The new edition of this landmark text continues to be the ‘one stop reference’ to pharmacology for Australian and New Zealand health science students. Chapters have been thoroughly updated and revised to include the latest information on the clinical use of drugs and their application to specific disciplines within the health professions is highlighted. Organised by body system, it retains the features that have proved popular with students and lecturers, such as Clinical Interest Boxes, Drug Monographs, chapter summaries and review exercises. The text gives a comprehensive introduction to important pharmacology principles and concepts and has a strong focus on therapeutics. Written specifically for the Australasian region, it reflects local generic drug names, availability and clinical uses, along with local aspects of scheduling, drug legislation and ethical issues.
1. UNIT 1 Introduction to Pharmacology - p. xxiv 2. Chapter 1 DRUGS AND MEDICINES - p. 1 3. Chapter 2 PHARMACOTHERAPY: CLINICAL USE OF DRUGS - p. 31 4. Chapter 3 OVER-THE-COUNTER DRUGS AND COMPLEMENTARY THERAPIES - p. 62 5. Chapter 4 LEGAL AND ETHICAL FOUNDATIONS OF PHARMACOTHERAPY - p. 92 6. UNIT 2 Principles of Pharmacology - p. 125 7. Chapter 5 MOLECULAR ASPECTS OF DRUG ACTION AND PHARMACODYNAMICS - p. 126 8. Chapter 6 DRUG ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION - p. 141 9. Chapter 7 PHARMACOGENETICS - p. 162 10. Chapter 8 PHARMACOKINETICS AND DOSING REGIMENS - p. 175 11. Chapter 9 INDIVIDUAL AND LIFESPAN ASPECTS OF DRUG THERAPY - p. 188 12. Chapter 10 ADVERSE DRUG REACTIONS AND DRUG INTERACTIONS - p. 203 13. Unit 3 Drugs Affecting the Peripheral Nervous System - p. 215 14. Chapter 11 OVERVIEW OF THE AUTONOMIC NERVOUS SYSTEM AND DRUGS AFFECTING CHOLINERGIC TRANSMISSION - p. 216 15. Chapter 12 OVERVIEW OF THE SYMPATHETIC NERVOUS SYSTEM AND DRUGS AFFECTING NORADRENERGIC TRANSMISSION - p. 234 16. Chapter 13 OVERVIEW OF THE SOMATIC NERVOUS SYSTEM AND DRUGS AFFECTING NEUROMUSCULAR TRANSMISSION - p. 253 17. Unit 4 Drugs Affecting the Central Nervous System - p. 265 18. Chapter 14 CENTRAL NERVOUS SYSTEM OVERVIEW AND ANAESTHETICS - p. 266 19. Chapter 15 ANALGESICS - p. 308 20. Chapter 16 ANTIANXIETY, SEDATIVE AND HYPNOTIC DRUGS - p. 340 21. Chapter 17 ANTIEPILEPTIC DRUGS - p. 356 22. Chapter 18 PSYCHOTROPIC AGENTS - p. 374 23. Chapter 19 CENTRAL NERVOUS SYSTEM STIMULANTS - p. 405 24. Chapter 20 DRUGS FOR NEURODEGENERATIVE DISORDERS AND HEADACHE - p. 416 25. Chapter 21 DRUG DEPENDENCE AND SOCIAL PHARMACOLOGY - p. 440 26. UNIT 5 Drugs Affecting the Heart and Vascular System - p. 483 27. Chapter 22 OVERVIEW OF THE HEART AND DRUGS AFFECTING CARDIAC FUNCTION - p. 484 28. Chapter 23 DRUGS AFFECTING VASCULAR SMOOTH MUSCLE - p. 512 29. Chapter 24 LIPID-LOWERING DRUGS - p. 536 30. UNIT 6 Drugs Affecting the Urinary System - p. 550 31. Chapter 25 DRUGS AFFECTING THE KIDNEY AND BLADDER - p. 551 32. UNIT 7 Drugs Affecting the Blood - p. 571 33. Chapter 26 DRUGS AFFECTING THROMBOSIS AND HAEMOSTASIS - p. 572 34. Chapter 27 DRUGS AFFECTING THE HAEMOPOIETIC SYSTEM - p. 592 35. UNIT 8 Drugs Affecting the Respiratory System - p. 599 36. Chapter 28 DRUGS USED IN RESPIRATORY DISORDERS - p. 600 37. UNIT 9 Drugs Affecting the Gastrointestinal System - p. 635 38. Chapter 29 DRUGS AFFECTING THE UPPER GASTROINTESTINAL TRACT - p. 636 39. Chapter 30 DRUGS AFFECTING THE LOWER GASTROINTESTINAL TRACT - p. 658 40. UNIT 10 Drugs Affecting the Eye, Ear and Special Senses - p. 669 41. Chapter 31 DRUGS AFFECTING THE EYE - p. 670 42. Chapter 32 DRUGS AFFECTING HEARING, TASTE AND SMELL - p. 697 43. UNIT 11 Drugs Affecting the Endocrine System - p. 708 44. Chapter 33 THE NEUROENDOCRINE SYSTEM AND PITUITARY GLAND - p. 709 45. Chapter 34 THE THYROID GLAND AND ANTITHYROID DRUGS - p. 727 46. Chapter 35 PHARMACOLOGY OF THE ADRENAL CORTEX - p. 741 47. Chapter 36 THE ENDOCRINE PANCREAS AND MANAGEMENT OF DIABETES MELLITUS - p. 756 48. Chapter 37 PHARMACOLOGY OF THE PARATHYROID GLANDS AND BONE - p. 780 49. UNIT 12 Drugs Affecting the Reproductive Systems - p. 796 50. Chapter 38 DRUGS AFFECTING THE FEMALE REPRODUCTIVE SYSTEM - p. 797 51. Chapter 39 DRUGS AFFECTING THE MALE REPRODUCTIVE SYSTEM - p. 823 52. Chapter 40 DRUGS AFFECTING FERTILITY OR SEXUAL FUNCTIONING - p. 833 53. UNIT 13 Drugs Used in Neoplastic Diseases - p. 856 54. Chapter 41 NEOPLASIA AND TREATMENT OF CANCERS - p. 857 55. Chapter 42 ANTINEOPLASTIC AGENTS AND ADJUNCTS - p. 880 56. UNIT 14 Drugs Affecting Microorganisms - p. 912 57. Chapter 43 OVERVIEW OF ANTIMICROBIAL CHEMOTHERAPY AND ANTIBIOTIC RESISTANCE - p. 913 58. Chapter 44 ANTIBACTERIAL DRUGS - p. 925 59. Chapter 45 ANTIFUNGAL AND ANTIVIRAL DRUGS - p. 946 60. Chapter 46 ANTIPROTOZOAL, ANTIMYCOBACTERIAL AND ANTHELMINTIC DRUGS - p. 968 61. UNIT 15 Drugs Affecting Body Defences - p. 988 62. Chapter 47 ANTI-INFLAMMATORY AND IMMUNOMODULATING DRUGS - p. 989 63. Chapter 48 DRUGS AFFECTING THE SKIN - p. 1021 64. UNIT 16 Special Topics - p. 1052 65. Chapter 49 DRUGS IN SPORT - p. 1053 66. Chapter 50 DRUGS IN OBESITY - p. 1072 67. Chapter 51 ENVENOMATION AND ANTIVENOMS - p. 1081 68. Appendixes - p. 1091 69. Appendix 1 ABBREVIATIONS - p. 1092 70. Appendix 2 ANTISEPTICS AND DISINFECTANTS - p. 1097 71. Appendix 3 HERB–, NUTRIENT– AND FOOD–DRUG INTERACTIONS - p. 1098 72. Appendix 4 GLOSSARY - p. 1100 73. Appendix 5 AUSTRALIAN POISONS STANDARD 2013 - p. 1107 74. Appendix 6 THE WORLD HEALTH ORGANIZATION MODEL LIST OF ESSENTIAL MEDICINES - p. 1109 75. FIGURE, TABLE AND PICTURE CREDITS - p. 1113 76. INDEX - p. 1114 77. INDEX - p. 1115 78. A - p. 1115 79. B - p. 1119 80. C - p. 1120 81. D - p. 1123 82. E - p. 1125 83. F - p. 1126 84. G - p. 1126 85. H - p. 1127 86. I - p. 1128 87. J - p. 1130 88. K - p. 1130 89. L - p. 1130 90. M - p. 1131 91. N - p. 1132 92. O - p. 1133 93. P - p. 1134 94. Q - p. 1137 95. R - p. 1137 96. S - p. 1138 97. T - p. 1140 98. U - p. 1141 99. V - p. 1142 100. W - p. 1142 101. X - p. 1142 102. Y - p. 1142 103. Z - p. 1142
