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This issue of Surgical Clinics of North America focuses on Surgical Critical Care, and is edited by Dr. Cynthia Talley. Articles will include: Brain Death; Indications and Methods of Anticoagulant Reversal; Ultrasound and Other Innovations for the ICU; Severe Sepsis Strategies; Renal Failure in the Critically Ill; Decompensated Cirrhosis and Fluid Resuscitation; Gastrointestinal Complications; Nutrition for the Critically Ill; End of Life and Goals of Care; Resuscitation for Hypovolemic Shock; Ventilator Strategies for COPD and ARDS; Traumatic Brain Injury Management; The Mobility and Impact of Frailty in the ICU; Delirium and PTSD Prevention; and more!

1. Introduction - p. 1339 2. Definitions - p. 1340 3. Pathophysiology - p. 1342 4. Diagnosis - p. 1343 5. Initial management: source control and antibiotic therapy - p. 1346 6. Initial management: resuscitation - p. 1347 7. Early goal-directed therapy versus standard therapy - p. 1349 8. Central venous pressure - p. 1351 9. Hemoglobin - p. 1352 10. Central venous oxygen saturation - p. 1352 11. Lactic acid - p. 1353 12. Mean arterial pressure - p. 1353 13. Summary: resuscitation strategy - p. 1354 14. Systems-based therapy - p. 1354 15. Summary - p. 1362 16. Ventilator Strategies for Chronic Obstructive Pulmonary Disease and Acute Respiratory Distress Syndrome - p. 1381 17. Acute Kidney Injury in the Critically Ill - p. 1399 18. Decompensated Cirrhosis and Fluid Resuscitation - p. 1419 19. Surgical Critical Care: Gastrointestinal Complications - p. 1425

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This issue of Surgical Clinics of North America focuses on Surgical Critical Care, and is edited by Dr. Cynthia Talley. Articles will include: Brain Death; Indications and Methods of Anticoagulant Reversal; Ultrasound and Other Innovations for the ICU; Severe Sepsis Strategies; Renal Failure in the Critically Ill; Decompensated Cirrhosis and Fluid Resuscitation; Gastrointestinal Complications; Nutrition for the Critically Ill; End of Life and Goals of Care; Resuscitation for Hypovolemic Shock; Ventilator Strategies for COPD and ARDS; Traumatic Brain Injury Management; The Mobility and Impact of Frailty in the ICU; Delirium and PTSD Prevention; and more!

1. Introduction - p. 1339 2. Definitions - p. 1340 3. Pathophysiology - p. 1342 4. Diagnosis - p. 1343 5. Initial management: source control and antibiotic therapy - p. 1346 6. Initial management: resuscitation - p. 1347 7. Early goal-directed therapy versus standard therapy - p. 1349 8. Central venous pressure - p. 1351 9. Hemoglobin - p. 1352 10. Central venous oxygen saturation - p. 1352 11. Lactic acid - p. 1353 12. Mean arterial pressure - p. 1353 13. Summary: resuscitation strategy - p. 1354 14. Systems-based therapy - p. 1354 15. Summary - p. 1362 16. Ventilator Strategies for Chronic Obstructive Pulmonary Disease and Acute Respiratory Distress Syndrome - p. 1381 17. Acute Kidney Injury in the Critically Ill - p. 1399 18. Decompensated Cirrhosis and Fluid Resuscitation - p. 1419 19. Surgical Critical Care: Gastrointestinal Complications - p. 1425

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