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Carcinogen-Driven Mouse Models of Oncogenesis, Volume 163 contains a series of protocols written by world-leading experts in the field. Each manuscript provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Chapters in this new release include Chemical carcinogenesis in mice as a model of human cancer: Pros and cons, MPA/DMBA-driven mammary carcinomas, Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice, Urethane-induced lung carcinogenesis, Methylcholanthrene-induced fibrosarcomas, BBN-driven bladder carcinomas, Oral squamous cell carcinomas driven by 4NQO, Analyzing skin tumor development in mice by the DMBA/TPA model, and much more.

Other sections cover DSS/AOM-driven colorectal carcinomas, Diethylnitrosamine-induced liver tumorigenesis in mice, Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice, Lung carcinomas induced by NNK and LPS, Pristane-induced mammary carcinomas, The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis, and more.

  • Provides protocols provided by renowned experts in the field
  • Presents detailed descriptions of protocols, hence allowing appropriate reproduction of the models
  • Includes author notes for each protocol, covering useful tips and troubleshooting

1. Cover image - p. page_i 2. Title page - p. page_i 3. Table of Contents - p. page_i 4. Copyright - p. page_iv 5. Contributors - p. page_xi 6. Preface: Chemical carcinogenesis in mice as a model of human cancer: Pros and cons - p. page_xvii 7. Chapter 1: MPA/DMBA-driven mammary carcinomas - p. page_1 8. Chapter 2: Dimethylbenz(a)anthracene-induced mammary tumorigenesis in mice - p. page_21 9. Chapter 3: Urethane-induced lung carcinogenesis - p. page_45 10. Chapter 4: Using methylcholanthrene-induced fibrosarcomas to study tumor immunology - p. page_59 11. Chapter 5: BBN-driven urinary bladder cancer mouse model - p. page_77 12. Chapter 6: 4NQO induced carcinogenesis: A mouse model for oral squamous cell carcinoma - p. page_93 13. Chapter 7: Analyzing skin tumor development in mice by the DMBA/TPA model - p. page_113 14. Chapter 8: Induction of colitis-associated neoplasia in mice using azoxymethane and dextran sodium sulfate - p. page_123 15. Chapter 9: Diethylnitrosamine-induced liver tumorigenesis in mice - p. page_137 16. Chapter 10: Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice - p. page_153 17. Chapter 11: Lung carcinomas induced by NNK and LPS - p. page_175 18. Chapter 12: Pristane-induced mammary carcinomas - p. page_187 19. Chapter 13: The 4-NQO mouse model: An update on a well-established in vivo model of oral carcinogenesis - p. page_197

Descripcion
Descripción

Carcinogen-Driven Mouse Models of Oncogenesis, Volume 163 contains a series of protocols written by world-leading experts in the field. Each manuscript provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Chapters in this new release include Chemical carcinogenesis in mice as a model of human cancer: Pros and cons, MPA/DMBA-driven mammary carcinomas, Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice, Urethane-induced lung carcinogenesis, Methylcholanthrene-induced fibrosarcomas, BBN-driven bladder carcinomas, Oral squamous cell carcinomas driven by 4NQO, Analyzing skin tumor development in mice by the DMBA/TPA model, and much more.

Other sections cover DSS/AOM-driven colorectal carcinomas, Diethylnitrosamine-induced liver tumorigenesis in mice, Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice, Lung carcinomas induced by NNK and LPS, Pristane-induced mammary carcinomas, The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis, and more.

  • Provides protocols provided by renowned experts in the field
  • Presents detailed descriptions of protocols, hence allowing appropriate reproduction of the models
  • Includes author notes for each protocol, covering useful tips and troubleshooting

1. Cover image - p. page_i 2. Title page - p. page_i 3. Table of Contents - p. page_i 4. Copyright - p. page_iv 5. Contributors - p. page_xi 6. Preface: Chemical carcinogenesis in mice as a model of human cancer: Pros and cons - p. page_xvii 7. Chapter 1: MPA/DMBA-driven mammary carcinomas - p. page_1 8. Chapter 2: Dimethylbenz(a)anthracene-induced mammary tumorigenesis in mice - p. page_21 9. Chapter 3: Urethane-induced lung carcinogenesis - p. page_45 10. Chapter 4: Using methylcholanthrene-induced fibrosarcomas to study tumor immunology - p. page_59 11. Chapter 5: BBN-driven urinary bladder cancer mouse model - p. page_77 12. Chapter 6: 4NQO induced carcinogenesis: A mouse model for oral squamous cell carcinoma - p. page_93 13. Chapter 7: Analyzing skin tumor development in mice by the DMBA/TPA model - p. page_113 14. Chapter 8: Induction of colitis-associated neoplasia in mice using azoxymethane and dextran sodium sulfate - p. page_123 15. Chapter 9: Diethylnitrosamine-induced liver tumorigenesis in mice - p. page_137 16. Chapter 10: Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice - p. page_153 17. Chapter 11: Lung carcinomas induced by NNK and LPS - p. page_175 18. Chapter 12: Pristane-induced mammary carcinomas - p. page_187 19. Chapter 13: The 4-NQO mouse model: An update on a well-established in vivo model of oral carcinogenesis - p. page_197

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