Extracellular Vesicles for Therapeutic and Diagnostic Applications provides an introduction to exosomes and extracellular vesicles, including their unique properties and characterization, before detailing the most-utilized isolation, purification, and surface engineering techniques for their preparation as therapeutic and diagnostic agents. This book reviews recent developments in interdisciplinary research on exosome structure, properties, and engineering approaches as well as their use in diagnosis and treatment of a variety of illnesses such as cancer, tuberculosis, Alzheimer's disease, ophthalmic diseases, and others. Extracellular Vesicles for Therapeutic and Diagnostic Applications is an important reference for those interested in the development and application of exosomes and extracellular vesicles as biomaterials for us in the diagnosis and treatment of disease.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xiii 7. Preface - p. xxi 8. Chapter 1. Isolation and purification of exosome and other extracellular vesicles - p. 1 9. Chapter 2. Overview of the characterization of extracellular vesicles - p. 25 10. Chapter 3. Extracellular vesicles for therapeutic and diagnostic applications - p. 57 11. Chapter 4. Preclinical evidence of extracellular vesicles for therapeutic and diagnostic applications - p. 81 12. Chapter 5. Extracellular vesicles as biomarker and therapeutic targets for neurological disorders - p. 105 13. Chapter 6. Revolutionizing cardiovascular health: exploring the extracellular vesicles - p. 139 14. Chapter 7. Extracellular vesicles for infectious diseases: a game-changer in infectious disease control - p. 157 15. Chapter 8. Extracellular vesicles against viral pathogens and infectious diseases - p. 175 16. Chapter 9. Theranostic potential of extracellular vesicles released from mycobacteria and mycobacterium-infected host cells - p. 205 17. Chapter 10. Extracellular vesicles in reproductive medicines - p. 243 18. Chapter 11. Extracellular vesicles for ophthalmic and dermal ailments - p. 283 19. Chapter 12. Extracellular vesicles for intervertebral disc regeneration - p. 347 20. Chapter 13. Extracellular vesicles: unlocking therapeutic potential in regenerative medicine - p. 397 21. Chapter 14. Role of extracellular vesicles in neurodegenerative diseases - p. 437 22. Chapter 15. Extracellular vesicle: the future personalized, targeted drug therapy towards cancer management - p. 453 23. Chapter 16. Exosome and other extracellular vesicles for bone diseases - p. 471 24. Chapter 17. In silico techniques, artificial intelligence, and machine learning for enhanced efficacy of extracellular vesicle–based diagnosis and therapeutics - p. 495 25. Chapter 18. Regulatory concerns for exosome- and other extracellular vesicle-based diagnostics and medicine products - p. 523 26. Index - p. 537
Extracellular Vesicles for Therapeutic and Diagnostic Applications provides an introduction to exosomes and extracellular vesicles, including their unique properties and characterization, before detailing the most-utilized isolation, purification, and surface engineering techniques for their preparation as therapeutic and diagnostic agents. This book reviews recent developments in interdisciplinary research on exosome structure, properties, and engineering approaches as well as their use in diagnosis and treatment of a variety of illnesses such as cancer, tuberculosis, Alzheimer's disease, ophthalmic diseases, and others. Extracellular Vesicles for Therapeutic and Diagnostic Applications is an important reference for those interested in the development and application of exosomes and extracellular vesicles as biomaterials for us in the diagnosis and treatment of disease.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xiii 7. Preface - p. xxi 8. Chapter 1. Isolation and purification of exosome and other extracellular vesicles - p. 1 9. Chapter 2. Overview of the characterization of extracellular vesicles - p. 25 10. Chapter 3. Extracellular vesicles for therapeutic and diagnostic applications - p. 57 11. Chapter 4. Preclinical evidence of extracellular vesicles for therapeutic and diagnostic applications - p. 81 12. Chapter 5. Extracellular vesicles as biomarker and therapeutic targets for neurological disorders - p. 105 13. Chapter 6. Revolutionizing cardiovascular health: exploring the extracellular vesicles - p. 139 14. Chapter 7. Extracellular vesicles for infectious diseases: a game-changer in infectious disease control - p. 157 15. Chapter 8. Extracellular vesicles against viral pathogens and infectious diseases - p. 175 16. Chapter 9. Theranostic potential of extracellular vesicles released from mycobacteria and mycobacterium-infected host cells - p. 205 17. Chapter 10. Extracellular vesicles in reproductive medicines - p. 243 18. Chapter 11. Extracellular vesicles for ophthalmic and dermal ailments - p. 283 19. Chapter 12. Extracellular vesicles for intervertebral disc regeneration - p. 347 20. Chapter 13. Extracellular vesicles: unlocking therapeutic potential in regenerative medicine - p. 397 21. Chapter 14. Role of extracellular vesicles in neurodegenerative diseases - p. 437 22. Chapter 15. Extracellular vesicle: the future personalized, targeted drug therapy towards cancer management - p. 453 23. Chapter 16. Exosome and other extracellular vesicles for bone diseases - p. 471 24. Chapter 17. In silico techniques, artificial intelligence, and machine learning for enhanced efficacy of extracellular vesicle–based diagnosis and therapeutics - p. 495 25. Chapter 18. Regulatory concerns for exosome- and other extracellular vesicle-based diagnostics and medicine products - p. 523 26. Index - p. 537
