Nucleic Acid Sensing and Immunity - PART A, Volume 344, provides a comprehensive overview of the nucleic acid machinery, from plants to mammalians, as well as their regulation. Specific chapters in this updated release include Molecular bases of discrimination between self from non-self nucleic acids, Intracellular RNA sensing in mammalian cells, Nuclear DNA damage and nucleic acid sensing, Negative regulation of nucleic acid sensing, Dendritic cell responses to exogenous nucleic acids, Activating the nucleic acid-sensing machinery for anticancer immunity, and Nucleic acid sensing and inflammasomes, amongst other topics.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. ix 6. Nucleic Acid Sensing at the Interface Between Innate and Adaptive Immunity - p. xi 7. Chapter One: Discrimination Between Self and Non-Self-Nucleic Acids by the Innate Immune System - p. xv 8. Chapter Two: Intracellular RNA Sensing in Mammalian Cells: Role in Stress Response and Cancer Therapies - p. 30 9. Chapter Three: Negative Regulation of Cytosolic Sensing of DNA - p. 89 10. Chapter Four: Nucleic Acid Sensing Perturbation: How Aberrant Recognition of Self-Nucleic Acids May Contribute to Autoimmune and Autoinflammatory Diseases - p. 115 11. Chapter Five: Common Differences: The Ability of Inflammasomes to Distinguish Between Self and Pathogen Nucleic Acids During Infection - p. 137 12. Chapter Six: Activating the Nucleic Acid-Sensing Machinery for Anticancer Immunity - p. 172 13. Chapter Seven: Cytosolic Nucleic Acid Sensors in Inflammatory and Autoimmune Disorders - p. 214
Nucleic Acid Sensing and Immunity - PART A, Volume 344, provides a comprehensive overview of the nucleic acid machinery, from plants to mammalians, as well as their regulation. Specific chapters in this updated release include Molecular bases of discrimination between self from non-self nucleic acids, Intracellular RNA sensing in mammalian cells, Nuclear DNA damage and nucleic acid sensing, Negative regulation of nucleic acid sensing, Dendritic cell responses to exogenous nucleic acids, Activating the nucleic acid-sensing machinery for anticancer immunity, and Nucleic acid sensing and inflammasomes, amongst other topics.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. ix 6. Nucleic Acid Sensing at the Interface Between Innate and Adaptive Immunity - p. xi 7. Chapter One: Discrimination Between Self and Non-Self-Nucleic Acids by the Innate Immune System - p. xv 8. Chapter Two: Intracellular RNA Sensing in Mammalian Cells: Role in Stress Response and Cancer Therapies - p. 30 9. Chapter Three: Negative Regulation of Cytosolic Sensing of DNA - p. 89 10. Chapter Four: Nucleic Acid Sensing Perturbation: How Aberrant Recognition of Self-Nucleic Acids May Contribute to Autoimmune and Autoinflammatory Diseases - p. 115 11. Chapter Five: Common Differences: The Ability of Inflammasomes to Distinguish Between Self and Pathogen Nucleic Acids During Infection - p. 137 12. Chapter Six: Activating the Nucleic Acid-Sensing Machinery for Anticancer Immunity - p. 172 13. Chapter Seven: Cytosolic Nucleic Acid Sensors in Inflammatory and Autoimmune Disorders - p. 214
