Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.
Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.
1. Introduction - p. 331 2. Native triterpenoids and their derivatives as scaffolds - p. 333 3. Transformations of triterpenoids by the functional groups - p. 334 4. Skeletal and oxidative transformations of triterpenoids - p. 348 5. Synthesis and transformations of other type triterpenoids based on betulin - p. 367 6. Synthesis of new triterpene hybrid molecules - p. 370 7. The biological activities and pharmacological properties of triterpenoids - p. 378 8. Conclusion - p. 397 9. List of abbreviations - p. 398 10. Acknowledgments - p. 398 11. References - p. 399 12. Chapter 11: Recent developments on the chemical and biological activity studies of dihydro-β-agarofuran sesquiterpenoids - p. 409 13. Abstract - p. 409 14. Introduction - p. 409 15. Classification and structures of naturally occurring dihydro-β-agarofuran sesquiterpenoids - p. 412 16. Isolation and structure elucidation - p. 459 17. Biological activities - p. 477 18. Conclusion - p. 481 19. List of abbreviations - p. 482 20. References - p. 482 21. Index - p. 486
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.
Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.
1. Introduction - p. 331 2. Native triterpenoids and their derivatives as scaffolds - p. 333 3. Transformations of triterpenoids by the functional groups - p. 334 4. Skeletal and oxidative transformations of triterpenoids - p. 348 5. Synthesis and transformations of other type triterpenoids based on betulin - p. 367 6. Synthesis of new triterpene hybrid molecules - p. 370 7. The biological activities and pharmacological properties of triterpenoids - p. 378 8. Conclusion - p. 397 9. List of abbreviations - p. 398 10. Acknowledgments - p. 398 11. References - p. 399 12. Chapter 11: Recent developments on the chemical and biological activity studies of dihydro-β-agarofuran sesquiterpenoids - p. 409 13. Abstract - p. 409 14. Introduction - p. 409 15. Classification and structures of naturally occurring dihydro-β-agarofuran sesquiterpenoids - p. 412 16. Isolation and structure elucidation - p. 459 17. Biological activities - p. 477 18. Conclusion - p. 481 19. List of abbreviations - p. 482 20. References - p. 482 21. Index - p. 486
