This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment.
1. Cover image - p. Cover 2. Title page - p. Cover 3. Table of Contents - p. Cover 4. Copyright - p. Cover 5. Dedication - p. Cover 6. PREFACE - p. v 7. Chapter 1: Teratology in the 20th century Environmental causes of congenital malformations in humans and how they were established - p. 135 8. 1 Introductory matters - p. 134 9. 2 Definitions - p. 136 10. 3 Classification - p. 139 11. 4 Frequency - p. 143 12. 5 Early human studies - p. 148 13. 6 Pioneering works - p. 157 14. 7 Early experiments - p. 159 15. 8 New challenges - p. 166 16. 9 Thalidomide - p. 167 17. 10 Testing for teratogenicity - p. 173 18. 11 Teratological detours - p. 175 19. 12 Surveillance of congenital malformations - p. 181 20. 13 Epidemiology of congenital malformations - p. 182 21. 14 Human disease as teratogen - p. 185 22. 15 Environmental hazards and disasters - p. 197 23. 16 Disease medication and teratogenesis - p. 210 24. 17 Folic acid and human malformations - p. 224 25. 18 Alcohol consumption during pregnancy - p. 237 26. 19 The accomplishment and the expectation - p. 255 27. Subject Index - p. 282
This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment.
1. Cover image - p. Cover 2. Title page - p. Cover 3. Table of Contents - p. Cover 4. Copyright - p. Cover 5. Dedication - p. Cover 6. PREFACE - p. v 7. Chapter 1: Teratology in the 20th century Environmental causes of congenital malformations in humans and how they were established - p. 135 8. 1 Introductory matters - p. 134 9. 2 Definitions - p. 136 10. 3 Classification - p. 139 11. 4 Frequency - p. 143 12. 5 Early human studies - p. 148 13. 6 Pioneering works - p. 157 14. 7 Early experiments - p. 159 15. 8 New challenges - p. 166 16. 9 Thalidomide - p. 167 17. 10 Testing for teratogenicity - p. 173 18. 11 Teratological detours - p. 175 19. 12 Surveillance of congenital malformations - p. 181 20. 13 Epidemiology of congenital malformations - p. 182 21. 14 Human disease as teratogen - p. 185 22. 15 Environmental hazards and disasters - p. 197 23. 16 Disease medication and teratogenesis - p. 210 24. 17 Folic acid and human malformations - p. 224 25. 18 Alcohol consumption during pregnancy - p. 237 26. 19 The accomplishment and the expectation - p. 255 27. Subject Index - p. 282
