This issue of Dermatologic Clinics, guest edited by Dr. John J. DiGiovanna, is devoted to Skin Science Contributions in Clinical Dermatology. Articles in this issue include Mosaic mTORopathies; CYLD: Cause and Therapeutic Target for Cylindromas; Current Status of Dedicator of Cytokinesis (DOCK), DOCK8, DOCK2; IL-22 relation to Tumor Aggression and Role of Cyclosporine; Dual Lineage of Dermal Fibroblasts and Potential for Scar Correction, Reformation of Adnexal Structures; Inflammasome Instigated Autoinflammatory Disorders; Pigment Cell Biology; Antimicrobial Peptides; and Choosing Friend or Foe? Commensal-specific tolerance.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Preface - p. ix 7. Antimicrobials, Immunity, and Inflammation: When to Do Battle, and How - p. x 8. Establishing Tolerance to Commensal Skin Bacteria: Timing Is Everything - p. 1 9. Current Status of Dedicator of Cytokinesis-Associated Immunodeficiency: DOCK8 and DOCK2 - p. 11 10. Dermatologic Manifestations of Monogenic Autoinflammatory Diseases - p. 21 11. The Critical and Multifunctional Roles of Antimicrobial Peptides in Dermatology - p. 39 12. Genetics, Lineage, and Malignancy - p. 50 13. Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway - p. 51 14. Understanding Inherited Cylindromas: Clinical Implications of Gene Discovery - p. 61 15. Interleukin-22 and Cyclosporine in Aggressive Cutaneous Squamous Cell Carcinoma - p. 73 16. Melanocytic Nevi and the Genetic and Epigenetic Control of Oncogene-Induced Senescence - p. 85 17. Distinct Fibroblasts in the Papillary and Reticular Dermis: Implications for Wound Healing - p. 95 18. Index - p. 101
This issue of Dermatologic Clinics, guest edited by Dr. John J. DiGiovanna, is devoted to Skin Science Contributions in Clinical Dermatology. Articles in this issue include Mosaic mTORopathies; CYLD: Cause and Therapeutic Target for Cylindromas; Current Status of Dedicator of Cytokinesis (DOCK), DOCK8, DOCK2; IL-22 relation to Tumor Aggression and Role of Cyclosporine; Dual Lineage of Dermal Fibroblasts and Potential for Scar Correction, Reformation of Adnexal Structures; Inflammasome Instigated Autoinflammatory Disorders; Pigment Cell Biology; Antimicrobial Peptides; and Choosing Friend or Foe? Commensal-specific tolerance.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Preface - p. ix 7. Antimicrobials, Immunity, and Inflammation: When to Do Battle, and How - p. x 8. Establishing Tolerance to Commensal Skin Bacteria: Timing Is Everything - p. 1 9. Current Status of Dedicator of Cytokinesis-Associated Immunodeficiency: DOCK8 and DOCK2 - p. 11 10. Dermatologic Manifestations of Monogenic Autoinflammatory Diseases - p. 21 11. The Critical and Multifunctional Roles of Antimicrobial Peptides in Dermatology - p. 39 12. Genetics, Lineage, and Malignancy - p. 50 13. Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway - p. 51 14. Understanding Inherited Cylindromas: Clinical Implications of Gene Discovery - p. 61 15. Interleukin-22 and Cyclosporine in Aggressive Cutaneous Squamous Cell Carcinoma - p. 73 16. Melanocytic Nevi and the Genetic and Epigenetic Control of Oncogene-Induced Senescence - p. 85 17. Distinct Fibroblasts in the Papillary and Reticular Dermis: Implications for Wound Healing - p. 95 18. Index - p. 101
