This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations.
1. Cover - p. 1 2. Contributors - p. 2 3. Contents - p. 3 4. Forthcoming Issues - p. 4 5. Mass Spectrometry Continues Its March into the Clinical Laboratory - p. 5 6. High-Flow Multiplexed MRM-Based Analysis of Proteins in Human Plasma Without Depletion or Enrichment - p. 6 7. Peptide Immunoaffinity Enrichment Coupled with Mass Spectrometry for Peptide and Protein Quantification - p. 11 8. The Analysis of Native Proteins and Peptides in the Clinical Lab Using Mass Spectrometry - p. 18 9. Mass Spectrometry for Clinical Toxicology: Therapeutic Drug Management and Trace Element Analysis - p. 22 10. High Throughput Automated LC-MS/MS Analysis of Endogenous Small Molecule Biomarkers - p. 33 11. Regulatory Considerations for Clinical Mass Spectrometry: Multiple Reaction Monitoring - p. 41 12. Erratum - p. 47 13. Index - p. 48
This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations.
1. Cover - p. 1 2. Contributors - p. 2 3. Contents - p. 3 4. Forthcoming Issues - p. 4 5. Mass Spectrometry Continues Its March into the Clinical Laboratory - p. 5 6. High-Flow Multiplexed MRM-Based Analysis of Proteins in Human Plasma Without Depletion or Enrichment - p. 6 7. Peptide Immunoaffinity Enrichment Coupled with Mass Spectrometry for Peptide and Protein Quantification - p. 11 8. The Analysis of Native Proteins and Peptides in the Clinical Lab Using Mass Spectrometry - p. 18 9. Mass Spectrometry for Clinical Toxicology: Therapeutic Drug Management and Trace Element Analysis - p. 22 10. High Throughput Automated LC-MS/MS Analysis of Endogenous Small Molecule Biomarkers - p. 33 11. Regulatory Considerations for Clinical Mass Spectrometry: Multiple Reaction Monitoring - p. 41 12. Erratum - p. 47 13. Index - p. 48
