Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource.
This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.
1. Phytopharmaceuticals and Herbal Drugs - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. Contributors - p. Page v 8. About the editors - p. Page viii 9. Foreword - p. Page ix 10. Preface - p. Page x 11. Acknowledgments - p. Page xii 12. List of Illustrations - p. Page xiii 13. List of Tables - p. Page xiv 14. Chapter 1 : Plant-based therapeutics: current status and future perspectives - p. Page xiv 15. Chapter 2 : Worldwide health scenario from the perspective of herbal medicine research - p. Page 10 16. Chapter 3 : Challenges in delivery of plant actives - p. Page 27 17. Chapter 4 : Lipid-based particulate systems for delivery of plant actives and extracts: Extraction, prospective carriers, and safety issues - p. Page 68 18. Chapter 5 : Phyto-complexed systems as a versatile tool for the delivery of plant-based drugs - p. Page 107 19. Chapter 6 : Impact of nanotechnology on herbal bioactives: an overview - p. Page 130 20. Chapter 7 : Application of nanomedicine for efficient delivery of herbal bioactives - p. Page 152 21. Chapter 8 : Nanophytomedicine: nanotechnology for herbal product development and value addition - p. Page 187 22. Chapter 9 : Phytopharmaceuticals and herbal drugs: prospects and safety issues in the delivery of natural products - p. Page 209 23. Chapter 10 : Herbal drug interaction and effects on phytopharmaceuticals - p. Page 246 24. Chapter 11 : Clinical, ethical, and regulatory issues of botanicals - p. Page 260 25. Chapter 12 : Commercial aspect and market potential of phytoactive products - p. Page 277 26. Chapter 13 : Interactions between radiopharmaceutical products and herbal medicines - p. Page 299 27. Chapter 14 : Use of microfluidic organ-on-a-chip systems for the screening and development of phytopharmaceuticals and herbal drugs - p. Page 320 28. Chapter 15 : New and revisited approaches on the transdermal delivery of polyphenols-loaded nanoparticles for melanoma prevention and treatment - p. Page 336 29. Chapter 16 : Novel drug delivery approaches for improving therapeutic applications of berberine and berberine-rich herbal preparations - p. Page 362 30. Chapter 17 : Impact of phytomedicines and their novel delivery systems as an alternative for the treatment of neurodegenerative disorders - p. Page 395 31. Chapter 18 : Role of phytopharmaceuticals in inflammatory disorders - p. Page 421 32. Index - p. Page 447
Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource.
This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.
1. Phytopharmaceuticals and Herbal Drugs - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. Contributors - p. Page v 8. About the editors - p. Page viii 9. Foreword - p. Page ix 10. Preface - p. Page x 11. Acknowledgments - p. Page xii 12. List of Illustrations - p. Page xiii 13. List of Tables - p. Page xiv 14. Chapter 1 : Plant-based therapeutics: current status and future perspectives - p. Page xiv 15. Chapter 2 : Worldwide health scenario from the perspective of herbal medicine research - p. Page 10 16. Chapter 3 : Challenges in delivery of plant actives - p. Page 27 17. Chapter 4 : Lipid-based particulate systems for delivery of plant actives and extracts: Extraction, prospective carriers, and safety issues - p. Page 68 18. Chapter 5 : Phyto-complexed systems as a versatile tool for the delivery of plant-based drugs - p. Page 107 19. Chapter 6 : Impact of nanotechnology on herbal bioactives: an overview - p. Page 130 20. Chapter 7 : Application of nanomedicine for efficient delivery of herbal bioactives - p. Page 152 21. Chapter 8 : Nanophytomedicine: nanotechnology for herbal product development and value addition - p. Page 187 22. Chapter 9 : Phytopharmaceuticals and herbal drugs: prospects and safety issues in the delivery of natural products - p. Page 209 23. Chapter 10 : Herbal drug interaction and effects on phytopharmaceuticals - p. Page 246 24. Chapter 11 : Clinical, ethical, and regulatory issues of botanicals - p. Page 260 25. Chapter 12 : Commercial aspect and market potential of phytoactive products - p. Page 277 26. Chapter 13 : Interactions between radiopharmaceutical products and herbal medicines - p. Page 299 27. Chapter 14 : Use of microfluidic organ-on-a-chip systems for the screening and development of phytopharmaceuticals and herbal drugs - p. Page 320 28. Chapter 15 : New and revisited approaches on the transdermal delivery of polyphenols-loaded nanoparticles for melanoma prevention and treatment - p. Page 336 29. Chapter 16 : Novel drug delivery approaches for improving therapeutic applications of berberine and berberine-rich herbal preparations - p. Page 362 30. Chapter 17 : Impact of phytomedicines and their novel delivery systems as an alternative for the treatment of neurodegenerative disorders - p. Page 395 31. Chapter 18 : Role of phytopharmaceuticals in inflammatory disorders - p. Page 421 32. Index - p. Page 447
