This issue of Immunology and Allergy Clinics of North America, guest edited by Dr. Rohit Katial, is devoted to Severe Asthma. Articles in this issue include: Epidemiology and Pulmonary Physiology of Severe Asthma; Linkage and Genetic Associations in Severe Asthma; Asthma COPD Overlap Syndrome (ACOS); Biomarkers in Severe Asthma; Imaging in Severe Asthma; Eosinophilic Phenotype; Neutrophilic and Pauci-immune Phenotypes; Role of Sleep Apnea and Gastroesophageal Reflux Disease in Severe Asthma; Role of Small Airways in Severe Asthma; Chronic Infection and Severe Asthma; Chronic Rhinosinusitis and Aspirin Associated Respiratory Disease; Psychosocial Factors in Severe Asthma; Traditional Therapies for Severe Asthma; and Emerging Biologics for Severe Asthma.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 6 7. Foreword: Severe Asthma: Chipping Away at the Unmet Need - p. 7 8. Preface: Severe Asthma: A Heterogeneous Disease - p. 8 9. Epidemiology and Pulmonary Physiology of Severe Asthma - p. 9 10. Linkage and Genetic Association in Severe Asthma - p. 17 11. Psychosocial Factors in Severe Pediatric Asthma - p. 21 12. Role of Sleep Apnea and Gastroesophageal Reflux in Severe Asthma - p. 28 13. Role of Small Airways in Asthma - p. 34 14. Chronic Infection and Severe Asthma - p. 39 15. Chronic Rhinosinusitis and Aspirin-Exacerbated Respiratory Disease - p. 50 16. Asthma–Chronic Obstructive Pulmonary Disease Overlap Syndrome - p. 55 17. Imaging of Asthma - p. 61 18. Biomarkers in Severe Asthma - p. 69 19. Eosinophilic Endotype of Asthma - p. 76 20. Neutrophilic and Pauci-immune Phenotypes in Severe Asthma - p. 83 21. Traditional Therapies for Severe Asthma - p. 88 22. Emerging Biologics in Severe Asthma - p. 102
This issue of Immunology and Allergy Clinics of North America, guest edited by Dr. Rohit Katial, is devoted to Severe Asthma. Articles in this issue include: Epidemiology and Pulmonary Physiology of Severe Asthma; Linkage and Genetic Associations in Severe Asthma; Asthma COPD Overlap Syndrome (ACOS); Biomarkers in Severe Asthma; Imaging in Severe Asthma; Eosinophilic Phenotype; Neutrophilic and Pauci-immune Phenotypes; Role of Sleep Apnea and Gastroesophageal Reflux Disease in Severe Asthma; Role of Small Airways in Severe Asthma; Chronic Infection and Severe Asthma; Chronic Rhinosinusitis and Aspirin Associated Respiratory Disease; Psychosocial Factors in Severe Asthma; Traditional Therapies for Severe Asthma; and Emerging Biologics for Severe Asthma.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 6 7. Foreword: Severe Asthma: Chipping Away at the Unmet Need - p. 7 8. Preface: Severe Asthma: A Heterogeneous Disease - p. 8 9. Epidemiology and Pulmonary Physiology of Severe Asthma - p. 9 10. Linkage and Genetic Association in Severe Asthma - p. 17 11. Psychosocial Factors in Severe Pediatric Asthma - p. 21 12. Role of Sleep Apnea and Gastroesophageal Reflux in Severe Asthma - p. 28 13. Role of Small Airways in Asthma - p. 34 14. Chronic Infection and Severe Asthma - p. 39 15. Chronic Rhinosinusitis and Aspirin-Exacerbated Respiratory Disease - p. 50 16. Asthma–Chronic Obstructive Pulmonary Disease Overlap Syndrome - p. 55 17. Imaging of Asthma - p. 61 18. Biomarkers in Severe Asthma - p. 69 19. Eosinophilic Endotype of Asthma - p. 76 20. Neutrophilic and Pauci-immune Phenotypes in Severe Asthma - p. 83 21. Traditional Therapies for Severe Asthma - p. 88 22. Emerging Biologics in Severe Asthma - p. 102