Microbiome and the Eye: What’s the connection? highlights how alterations in the gut and eye microbiomes can lead to systemic immune alterations with subsequent effects on the eye. The book is divided into two sections, one highlighting how alterations in the gut microbiome impact various components of health outside the gut, with a focus on the immune system and inflammatory mediators, and the second focusing on studies on a variety of ocular diseases, including ocular surface diseases/dry eye, keratitis, uveitis, glaucoma, and retinopathy to gut dysbiosis. With its translational approach, the book is suitable for both researchers and clinicians.
The book will help readers understand the mechanisms in which gut and eye microbiome composition may influence health in multiple compartments, with a focus on eye diseases.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. ix 7. Part 1: How does the microbiome influence human health - p. xi 8. Chapter One. The “normal” gut microbiome and human health - p. 3 9. Chapter Two. Structural and functional variation of human oral microbiome in health and disease - p. 19 10. Chapter Three. The “normal” ocular microbiome and human eye health - p. 87 11. Chapter Four. What is microbial dysbiosis and how does it impact human health? - p. 109 12. Chapter Five. Immune response to intestinal microbial dysbiosis - p. 125 13. Part 2: Microbiome alterations and eye disease - p. 132 14. Chapter Six. The impact of microbiome alterations on ocular surface diseases - p. 139 15. Chapter Seven. The microbiome and keratitis - p. 159 16. Chapter EIGHT. Seven reasons for a uveitis specialist to understand the microbiome - p. 163 17. Chapter Nine. Influence of gut microbiome on primary open angle glaucoma - p. 175 18. Chapter Ten. Microbiome abnormalities and retinal disease - p. 181 19. Chapter Eleven. Microbiome manipulation as a target for eye diseases: Lessons from animal models - p. 197 20. Chapter Twelve. Microbiome manipulation as a target for eye diseases: lessons from humans - p. 205 21. Index - p. 223
Microbiome and the Eye: What’s the connection? highlights how alterations in the gut and eye microbiomes can lead to systemic immune alterations with subsequent effects on the eye. The book is divided into two sections, one highlighting how alterations in the gut microbiome impact various components of health outside the gut, with a focus on the immune system and inflammatory mediators, and the second focusing on studies on a variety of ocular diseases, including ocular surface diseases/dry eye, keratitis, uveitis, glaucoma, and retinopathy to gut dysbiosis. With its translational approach, the book is suitable for both researchers and clinicians.
The book will help readers understand the mechanisms in which gut and eye microbiome composition may influence health in multiple compartments, with a focus on eye diseases.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. ix 7. Part 1: How does the microbiome influence human health - p. xi 8. Chapter One. The “normal” gut microbiome and human health - p. 3 9. Chapter Two. Structural and functional variation of human oral microbiome in health and disease - p. 19 10. Chapter Three. The “normal” ocular microbiome and human eye health - p. 87 11. Chapter Four. What is microbial dysbiosis and how does it impact human health? - p. 109 12. Chapter Five. Immune response to intestinal microbial dysbiosis - p. 125 13. Part 2: Microbiome alterations and eye disease - p. 132 14. Chapter Six. The impact of microbiome alterations on ocular surface diseases - p. 139 15. Chapter Seven. The microbiome and keratitis - p. 159 16. Chapter EIGHT. Seven reasons for a uveitis specialist to understand the microbiome - p. 163 17. Chapter Nine. Influence of gut microbiome on primary open angle glaucoma - p. 175 18. Chapter Ten. Microbiome abnormalities and retinal disease - p. 181 19. Chapter Eleven. Microbiome manipulation as a target for eye diseases: Lessons from animal models - p. 197 20. Chapter Twelve. Microbiome manipulation as a target for eye diseases: lessons from humans - p. 205 21. Index - p. 223
