Year Book of Pathology and Laboratory Medicine 2013

1. The Brain-to-Brain Loop Concept for Laboratory Testing 40 Years After Its Introduction - p. 184 2. Staffing Benchmarks for Clinical Laboratories: A College of American Pathologists Q-Probes Study of Laboratory Staffing at 98 Institutions - p. 185 3. A Decision-Tree Approach to Cost Comparison of Newborn Screening Strategies for Cystic Fibrosis - p. 186 4. A cost-effectiveness model of genetic testing for the evaluation of families with hypertrophic cardiomyopathy - p. 187 5. College of American Pathologists Proposal for the Oversight of Laboratory-Developed Tests - p. 188 6. Challenges and Opportunities in the Application Process for Fellowship Training in Pathology: An Independent Survey of Residents and Fellows Demonstrates Limited Interest in an NRMP-Style Matching Program - p. 189 7. Electronic health record donations by laboratories: Is legal necessarily ethical? - p. 190 8. The Long and Winding Regulatory Road for Laboratory-Developed Tests - p. 191 9. Bridging the Chasm: Effect of Health Information Exchange on Volume of Laboratory Testing - p. 192 10. A Consensus Curriculum for Laboratory Management Training for Pathology Residents - p. 193 11. 17. Clinical Chemistry - p. 194 12. Closing the Gaps in Pediatric Laboratory Reference Intervals: A CALIPER Database of 40 Biochemical Markers in a Healthy and Multiethnic Population of Children - p. 195 13. Should I Repeat My 1:2s QC Rejection? - p. 196 14. A Review of the Methods, Interpretation, and Limitations of the Urine Drug Screen - p. 197 15. Colonoscopy versus Fecal Immunochemical Testing in Colorectal-Cancer Screening - p. 198 16. A comparison of plasma-free metanephrines with plasma catecholamines in the investigation of suspected pheochromocytoma - p. 199 17. Evaluation of the Test-mate ChE (Cholinesterase) Field Kit in Acute Organophosphorus Poisoning - p. 200 18. An Examination of the Usefulness of Repeat Testing Practices in a Large Hospital Clinical Chemistry Laboratory - p. 201 19. Accuracy of 6 Routine 25-Hydroxyvitamin D Assays: Influence of Vitamin D Binding Protein Concentration - p. 202 20. Comparison of Serum Creatinine and Cystatin C for Early Diagnosis of Contrast-Induced Nephropathy after Coronary Angiography and Interventions - p. 203 21. Long-Term Biological Variation of Serum Protein Electrophoresis M-Spike, Urine M-Spike, and Monoclonal Serum Free Light Chain Quantification: Implications for Monitoring Monoclonal Gammopathies - p. 204 22. Investigating Interferences of a Whole-Blood Point-of-Care Creatinine Analyzer: Comparison to Plasma Enzymatic and Definitive Creatinine Methods in an Acute-Care Setting - p. 205 23. 18. Clinical Microbiology - p. 206 24. Visual Detection of High-Risk Human Papillomavirus Genotypes 16, 18, 45, 52, and 58 by Loop-Mediated Isothermal Amplification with Hydroxynaphthol Blue Dye - p. 207 25. Rapid Identification of Staphylococcus aureus and Methicillin Resistance by Flow Cytometry Using a Peptide Nucleic Acid Probe - p. 208 26. Identification of False-Positive QuantiFERON-TB Gold In-Tube Assays by Repeat Testing in HIV-Infected Patients at Low Risk for Tuberculosis - p. 209 27. A Critical Appraisal of the Role of the Clinical Microbiology Laboratory in the Diagnosis of Bloodstream Infections - p. 210 28. Accuracy of microscopic urine analysis and chest radiography in patients with severe sepsis and septic shock - p. 211 29. Trends and Characteristics of Culture-Confirmed Staphylococcus aureus Infections in a Large U.S. Integrated Health Care Organization - p. 212 30. Invasive Mycoses: Diagnostic Challenges - p. 213 31. A Highly Efficient Ziehl-Neelsen stain: Identifying De Novo Intracellular Mycobacterium tuberculosis and Improving Detection of Extracellular M. tuberculosis in Cerebrospinal Fluid - p. 214 32. A Sample Extraction Method for Faster, More Sensitive PCR-Based Detection of Pathogens in Blood Culture - p. 215 33. Bacteriuria Screening by Automated Whole-Field-Image-Based Microscopy Reduces the Number of Necessary Urine Cultures - p. 216 34. A Critical Appraisal of the Role of the Clinical Microbiology Laboratory in the Diagnosis of Urinary Tract Infections - p. 217 35. 19. Hematology and Immunology - p. 218 36. Using the Antinuclear Antibody Test to Diagnose Rheumatic Diseases: When Does a Positive Test Warrant Further Investigation? - p. 219 37. Expression of Hemoglobin Variant Migration by Capillary Electrophoresis Relative to Hemoglobin A2 Improves Precision - p. 220 38. Is the Blood Basophil Count Sufficiently Precise, Accurate, and Specific?: Three Automated Hematology Instruments and Flow Cytometry Compared - p. 221 39. Low activated leukocyte cell adhesion molecule expression is associated with advanced tumor stage and early prostate-specific antigen relapse in prostate cancer - p. 222 40. Cytogenetic Profile of Patients With Acute Myeloid Leukemia and Central Nervous System Disease - p. 223 41. Predictive Parameters for a Diagnostic Bone Marrow Biopsy Specimen in the Work-Up of Fever of Unknown Origin - p. 224 42. Early Cytogenetic and Molecular Response During First-Line Treatment of Chronic Myeloid Leukemia in Chronic Phase: Long-Term Implications - p. 225 43. Detection of Leukemic Lymphoblasts in CSF Is Instrument-Dependent - p. 226 44. Translational Applications of Flow Cytometry in Clinical Practice - p. 227 45. Prognostic Impact of Discordant Results From Cytogenetics and Flow Cytometry in Patients With Acute Myeloid Leukemia Undergoing Hematopoietic Cell Transplantation - p. 228 46. A prospective randomised study of a rotary powered device (OnControl) for bone marrow aspiration and biopsy - p. 229 47. Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia - p. 230 48. Cytogenetic Profile of Patients With Acute Myeloid Leukemia and Central Nervous System Disease - p. 231 49. Expanding Nilotinib Access in Clinical Trials (ENACT): An Open-Label, Multicenter Study of Oral Nilotinib in Adult Patients With Imatinib-Resistant or Imatinib-Intolerant Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in the Chronic Phase - p. 232 50. A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis - p. 233 51. CD117 Expression Is a Sensitive but Nonspecific Predictor of FLT3 Mutation in T Acute Lymphoblastic Leukemia and T/Myeloid Acute Leukemia - p. 234 52. Prognostic Value of MYC Rearrangement in Cases of B-cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma - p. 235 53. Blockade of Lymphocyte Chemotaxis in Visceral Graft-Versus-Host Disease - p. 236 54. Predicting Survival of Patients With Hypocellular Myelodysplastic Syndrome: Development of a Disease-Specific Prognostic Score System - p. 237 55. Eltrombopag and Improved Hematopoiesis in Refractory Aplastic Anemia - p. 238 56. Molecular and Clinicopathologic Characterization of AML With Isolated Trisomy 4 - p. 239 57. The Role of CD19 and CD27 in the Diagnosis of Multiple Myeloma by Flow Cytometry: A New Statistical Model - p. 240 58. 20. Transfusion Medicine and Coagulation - p. 241 59. Whole blood gene expression analyses in patients with single versus recurrent venous thromboembolism - p. 242 60. A Diagnosis of Heparin-Induced Thrombocytopenia with Combined Clinical and Laboratory Methods in Cardiothoracic Surgical Intensive Care Unit Patients - p. 243 61. Report of the first nationally implemented clinical routine screening for fetal RHD in D− pregnant women to ascertain the requirement for antenatal RhD prophylaxis - p. 244 62. Is current serologic RhD typing of blood donors sufficient for avoiding immunization of recipients? - p. 245 63. In vitro properties of platelets stored in three different additive solutions - p. 246 64. Detection of bacterial contamination in prestorage culture-negative apheresis platelets on day of issue with the Pan Genera Detection test - p. 247 65. Normal range of mean platelet volume in healthy subjects: Insight from a large epidemiologic study - p. 248 66. Blood platelet biochemistry - p. 249 67. A flow cytometric method for platelet counting in platelet concentrates - p. 250 68. New allele-specific real-time PCR system for warfarin dose genotyping equipped with an automatic interpretative function that allows rapid, accurate, and user-friendly reporting in clinical laboratories - p. 251 69. Development of an ethidium monoazide–enhanced internally controlled universal 16S rDNA real-time polymerase chain reaction assay for detection of bacterial contamination in platelet concentrates - p. 252 70. Artificial microvascular network: a new tool for measuring rheologic properties of stored red blood cells - p. 253 71. Molecular blood typing augments serologic testing and allows for enhanced matching of red blood cells for transfusion in patients with sickle cell disease - p. 254 72. Transfusion of older stored blood and risk of death: a meta analysis - p. 255 73. In vitro platelet quality in storage containers used for pediatric transfusions - p. 256 74. Measuring Direct Thrombin Inhibitors With Routine and Dedicated Coagulation Assays: Which Assay Is Helpful? - p. 257 75. Polymerase chain reaction–based tests for pan-species and species-specific detection of human Plasmodium parasites - p. 258 76. A Massive Transfusion Protocol Incorporating a Higher FFP/RBC Ratio Is Associated With Decreased Use of Recombinant Activated Factor VII in Trauma Patients - p. 259 77. Epidemiologic and laboratory findings from 3 years of testing United States blood donors for Trypanosoma cruzi - p. 260 78. Storage time of blood products and transfusion-related acute lung injury - p. 261 79. Flow cytometry assessment of apoptotic CD34+ cells by annexin V labeling may improve prediction of cord blood potency for engraftment - p. 262 80. Treatment of whole blood with riboflavin plus ultraviolet light, an alternative to gamma irradiation in the prevention of transfusion-associated graft-versus-host disease? - p. 263 81. The clinical relevance of persistent recombinant immunoblot assay–indeterminate reactions: insights into the natural history of hepatitis C virus infection and implications for donor counseling - p. 264 82. Report of the first nationally implemented clinical routine screening for fetal RHD in D− pregnant women to ascertain the requirement for antenatal RhD prophylaxis - p. 265 83. Comparative in vitro evaluation of apheresis platelets stored with 100% plasma or 65% platelet additive solution III/35% plasma and including periods without agitation under simulated shipping conditions - p. 266 84. 21. Cytogenetics and Molecular Pathology - p. 267 85. Digital PCR Analysis of Maternal Plasma for Noninvasive Detection of Sickle Cell Anemia - p. 268 86. Newborn Screening for Spinal Muscular Atrophy by Calibrated Short-Amplicon Melt Profiling - p. 269 87. Development of Plasmid Calibrators for Absolute Quantification of miRNAs by Using Real-Time qPCR - p. 270 88. Performance and Clinical Evaluation of the 92-Gene Real-Time PCR Assay for Tumor Classification - p. 271 89. Influence of RNA Labeling on Expression Profiling of MicroRNAs - p. 272 90. Mutant Enrichment with 3′-Modified Oligonucleotides: A Practical PCR Method for Detecting Trace Mutant DNAs - p. 273 91. Novel, Improved Sample Preparation for Rapid, Direct Identification from Positive Blood Cultures Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry - p. 274 92. Design and Analytical Validation of Clinical DNA Sequencing Assays - p. 275 93. A Locked Nucleic Acid Clamp-Mediated PCR Assay for Detection of a p53 Codon 249 Hotspot Mutation in Urine - p. 276 94. Proof of Concept Study to Assess Fetal Gene Expression in Amniotic Fluid by NanoArray PCR - p. 277 95. Identification of Recombinant Alleles Using Quantitative Real-Time PCR: Implications for Gaucher Disease - p. 278