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Dr. Pyrsopoulos has assembled the top authors in the field to provide current reviews on acute liver failure, to be the first time this topic is addressed in one volume. Topics are devoted to Classification and Epidemiologic Aspects of Acute Liver Failure; Acute Liver Failure: Mechanisms of disease and multi-systemic involvement; The Pathology of Acute Liver Failure; Liver Regeneration in the Acute Liver Failure Patient; Viral Hepatitis and Acute Liver Failure: Still a Problem; Drug- induced Liver Injury and Acute Liver Failure; Acetaminophen and Acute Liver Failure; Non-Viral Or Drug-Induced Etiologies of Acute Liver Failure; The Clinical Spectrum and Manifestations of Acute Liver Failure; Non ICU Management of Acute Liver Failure; Management of Acute Liver Failure in the ICU Setting; Prognostic Models of Acute Liver Failure; The Role of Liver Transplantation in Acute Liver Failure; and Future Approaches and Therapeutic Modalities for Acute Liver Failure. Readers will come away with a current point of view about how to approach and manage the patient with acute liver failure.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Classification and Epidemiologic Aspects of Acute Liver Failure - p. 229 9. Acute Liver Failure: Mechanisms of Disease and Multisystemic Involvement - p. 243 10. The Pathology of Acute Liver Failure - p. 257 11. Liver Regeneration in the Acute Liver Failure Patient - p. 269 12. Viral Hepatitis and Acute Liver Failure: Still a Problem - p. 289 13. Nonacetaminophen Drug-Induced Acute Liver Failure - p. 301 14. Acetaminophen (APAP or N-Acetyl-p-Aminophenol) and Acute Liver Failure - p. 325 15. Nonviral or Drug-Induced Etiologies of Acute Liver Failure - p. 347 16. The Clinical Spectrum and Manifestations of Acute Liver Failure - p. 361 17. Prognostic Models in Acute Liver Failure - p. 375 18. Non–Intensive Care Unit Management of Acute Liver Failure - p. 389 19. Management of Acute Liver Failure in the Intensive Care Unit Setting - p. 403 20. Liver Transplantation for Acute Liver Failure - p. 409 21. Future Approaches and Therapeutic Modalities for Acute Liver Failure - p. 419

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Dr. Pyrsopoulos has assembled the top authors in the field to provide current reviews on acute liver failure, to be the first time this topic is addressed in one volume. Topics are devoted to Classification and Epidemiologic Aspects of Acute Liver Failure; Acute Liver Failure: Mechanisms of disease and multi-systemic involvement; The Pathology of Acute Liver Failure; Liver Regeneration in the Acute Liver Failure Patient; Viral Hepatitis and Acute Liver Failure: Still a Problem; Drug- induced Liver Injury and Acute Liver Failure; Acetaminophen and Acute Liver Failure; Non-Viral Or Drug-Induced Etiologies of Acute Liver Failure; The Clinical Spectrum and Manifestations of Acute Liver Failure; Non ICU Management of Acute Liver Failure; Management of Acute Liver Failure in the ICU Setting; Prognostic Models of Acute Liver Failure; The Role of Liver Transplantation in Acute Liver Failure; and Future Approaches and Therapeutic Modalities for Acute Liver Failure. Readers will come away with a current point of view about how to approach and manage the patient with acute liver failure.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Classification and Epidemiologic Aspects of Acute Liver Failure - p. 229 9. Acute Liver Failure: Mechanisms of Disease and Multisystemic Involvement - p. 243 10. The Pathology of Acute Liver Failure - p. 257 11. Liver Regeneration in the Acute Liver Failure Patient - p. 269 12. Viral Hepatitis and Acute Liver Failure: Still a Problem - p. 289 13. Nonacetaminophen Drug-Induced Acute Liver Failure - p. 301 14. Acetaminophen (APAP or N-Acetyl-p-Aminophenol) and Acute Liver Failure - p. 325 15. Nonviral or Drug-Induced Etiologies of Acute Liver Failure - p. 347 16. The Clinical Spectrum and Manifestations of Acute Liver Failure - p. 361 17. Prognostic Models in Acute Liver Failure - p. 375 18. Non–Intensive Care Unit Management of Acute Liver Failure - p. 389 19. Management of Acute Liver Failure in the Intensive Care Unit Setting - p. 403 20. Liver Transplantation for Acute Liver Failure - p. 409 21. Future Approaches and Therapeutic Modalities for Acute Liver Failure - p. 419

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