Brody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives.
What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.
1. Chapter 1: Introduction - p. xi 2. Chapter 2: Cellular Receptors and Drug Concentration–Response Relationships - p. 3 3. Chapter 3: Pharmacokinetics - p. 20 4. Chapter 4: Pharmacogenetics - p. 40 5. Chapter 5: Drug Discovery, Development, and Regulation - p. 48 6. Section 2: Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses - p. 56 7. Chapter 6: Introduction to the Autonomic Nervous System - p. 56 8. Cholinergic Drugs - p. 67 9. Chapter 7: Muscarinic Agonists, Cholinesterase Inhibitors, and Their Clinical Uses - p. 67 10. Chapter 8: Muscarinic Antagonists and Their Clinical Uses - p. 78 11. Chapter 9: Nicotinic Agonists and Their Clinical Uses - p. 83 12. Chapter 10: Neuromuscular Blocking Drugs and Nicotinic Antagonists - p. 87 13. Adrenergic Drugs - p. 94 14. Chapter 11: Adrenergic Agonists and Their Clinical Uses - p. 94 15. Chapter 12: Adrenergic Antagonists and Their Clinical Uses - p. 106 16. Section 3: Drug Treatment for Disorders Affecting the Central Nervous System - p. 115 17. Chapter 13: The Central Nervous System - p. 115 18. Chapter 14: Drug Therapy for Alzheimer Disease and Other Cognitive Disorders/Dementias - p. 128 19. Chapter 15: Pharmacotherapy of Basal Ganglia Disorders: Parkinson Disease and Huntington Disease - p. 135 20. Chapter 16: Drug Therapy for Psychoses and Bipolar Disorder - p. 144 21. Chapter 17: Drug Therapy for Depression and Anxiety - p. 153 22. Chapter 18: Drug Therapy for the Management of Attention Deficit-Hyperactivity Disorder - p. 168 23. Chapter 19: Drug Therapy for Insomnia and the Hypersomnias - p. 177 24. Chapter 20: Drug Therapy for Managing Obesity and Eating Disorders - p. 185 25. Chapter 21: Treatment of Seizure Disorders - p. 191 26. Chapter 22: Drug Therapy for Spasticity Disorders - p. 206 27. Chapter 23: Ethanol, Other Alcohols, and Medications for Alcohol Use Disorder - p. 212 28. Chapter 24: Psychoactive Compounds and Substance Use Disorder - p. 222 29. Section 4: Drug Therapy for Pain Management - p. 235 30. Chapter 25: Introduction - p. 235 31. Chapter 26: General Anesthetics - p. 240 32. Chapter 27: Local Anesthetics - p. 251 33. Chapter 28: Opioid Analgesics - p. 259 34. Chapter 29: Nonsteroidal Antiinflammatory Drugs and Acetaminophen - p. 268 35. Chapter 30: Cannabinoids - p. 276 36. Chapter 31: Drug Therapy for Migraine Headache - p. 283 37. Section 5: Treatment of Inflammatory, Allergic and Immunologic Disorders - p. 291 38. Chapter 32: Drug Therapy for Gout and Hyperuricemia - p. 291 39. Chapter 33: Pharmacological Interventions for Allergic Reactions - p. 297 40. Chapter 34: Immunosuppressants for Autoimmune Disorders and Organ Transplantation - p. 305 41. Chapter 35: Drug Therapy for Rheumatoid Arthritis - p. 313 42. Section 6: Drug Treatment for Cardiovascular Diseases - p. 320 43. Chapter 36: Introduction to the Regulation of Cardiovascular Function - p. 320 44. Chapter 37: Overview of Hypertension Management and Drugs That Decrease Sympathetic Tone - p. 326 45. Chapter 38: Diuretics and Drugs That Affect Volume and Electrolyte Content - p. 332 46. Chapter 39: Drugs Affecting the Renin-Angiotensin-Aldosterone System - p. 347 47. Chapter 40: Calcium-Channel Blockers - p. 353 48. Chapter 41: Vasodilators for Hypertensive Crises, Pulmonary Hypertension, and Erectile Dysfunction - p. 358 49. Chapter 42: Treatment of Hyperlipidemias and Atherosclerotic Cardiovascular Disease - p. 366 50. Chapter 43: Treatment of Myocardial Ischemia and Angina Pectoris - p. 377 51. Chapter 44: Treatment of Heart Failure - p. 383 52. Chapter 45: Antiarrhythmic Drugs - p. 391 53. Chapter 46: Anticoagulant, Antiplatelet, and Fibrinolytic Medications - p. 405 54. Chapter 47: Drug Therapy for Hemophilia and the Deficiency Anemias - p. 415 55. Section 7: Treatment of Endocrine Disorders - p. 422 56. Chapter 48: Introduction to Endocrine Pharmacology - p. 422 57. Chapter 49: Treatment of Hypothalamic and Pituitary Disorders - p. 427 58. Chapter 50: Diagnosis and Treatment of Adrenocorticosteroid Disorders - p. 436 59. Chapter 51: Female Hormone Regulation - p. 445 60. Chapter 52: Androgens, Antiandrogens, and Their Clinical Uses - p. 461 61. Chapter 53: Drug Therapy for the Management of Diabetes - p. 468 62. Chapter 54: Drug Therapy for the Management of Thyroid Disorders - p. 484 63. Chapter 55: Calcium Regulating Hormones and Other Agents Affecting Bone - p. 493 64. Section 8: Chemotherapy - p. 503 65. Infectious Diseases - p. 503 66. Chapter 56: Principles of Antimicrobial Use - p. 503 67. Chapter 57: Drugs Targeting Bacterial Cell Walls and Membranes - p. 520 68. Chapter 58: Drugs Targeting Bacterial Protein Synthesis - p. 536 69. Chapter 59: Drugs Targeting Bacterial DNA - p. 550 70. Chapter 60: Antimycobacterial Agents - p. 559 71. Chapter 61: Drugs Targeting Resistant Organisms - p. 568 72. Parasitic Diseases - p. 574 73. Chapter 62: Antifungal Agents - p. 574 74. Chapter 63: Antimalarial and Other Antiprotozoal Agents - p. 584 75. Chapter 64: Anthelmintics and Ectoparasiticides - p. 595 76. Viruses - p. 601 77. Chapter 65: Antiviral Agents - p. 601 78. Chapter 66: Antiretroviral Drugs for HIV - p. 612 79. Cancer - p. 622 80. Chapter 67: Principles of Cancer and Antineoplastic Drug Use - p. 622 81. Chapter 68: Cytotoxic Agents - p. 631 82. Chapter 69: Targeted Anticancer Agents - p. 650 83. Chapter 70: Immunological and Cell-Based Therapies - p. 662 84. Section 9: Special Considerations - p. 670 85. Chapter 71: Therapeutic Use of Hematopoietic Growth Factors - p. 670 86. Chapter 72: Gastrointestinal Disorders and Their Treatment - p. 676 87. Chapter 73: Pharmacological Interventions for Asthma and Chronic Obstructive Pulmonary Disorders - p. 687 88. Chapter 74: Dietary Supplements, Nutraceuticals, and Natural Products - p. 698 89. Chapter 75: Essentials of Toxicology - p. 705 90. Chapter 76: Therapeutic Considerations for Pregnant, Pediatric, Geriatric, and Obese Individuals - p. 710 91. Appendix - p. 715 92. Index - p. 728 93. Confidence is ClinicalKey - p. 728
Brody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives.
What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.
1. Chapter 1: Introduction - p. xi 2. Chapter 2: Cellular Receptors and Drug Concentration–Response Relationships - p. 3 3. Chapter 3: Pharmacokinetics - p. 20 4. Chapter 4: Pharmacogenetics - p. 40 5. Chapter 5: Drug Discovery, Development, and Regulation - p. 48 6. Section 2: Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses - p. 56 7. Chapter 6: Introduction to the Autonomic Nervous System - p. 56 8. Cholinergic Drugs - p. 67 9. Chapter 7: Muscarinic Agonists, Cholinesterase Inhibitors, and Their Clinical Uses - p. 67 10. Chapter 8: Muscarinic Antagonists and Their Clinical Uses - p. 78 11. Chapter 9: Nicotinic Agonists and Their Clinical Uses - p. 83 12. Chapter 10: Neuromuscular Blocking Drugs and Nicotinic Antagonists - p. 87 13. Adrenergic Drugs - p. 94 14. Chapter 11: Adrenergic Agonists and Their Clinical Uses - p. 94 15. Chapter 12: Adrenergic Antagonists and Their Clinical Uses - p. 106 16. Section 3: Drug Treatment for Disorders Affecting the Central Nervous System - p. 115 17. Chapter 13: The Central Nervous System - p. 115 18. Chapter 14: Drug Therapy for Alzheimer Disease and Other Cognitive Disorders/Dementias - p. 128 19. Chapter 15: Pharmacotherapy of Basal Ganglia Disorders: Parkinson Disease and Huntington Disease - p. 135 20. Chapter 16: Drug Therapy for Psychoses and Bipolar Disorder - p. 144 21. Chapter 17: Drug Therapy for Depression and Anxiety - p. 153 22. Chapter 18: Drug Therapy for the Management of Attention Deficit-Hyperactivity Disorder - p. 168 23. Chapter 19: Drug Therapy for Insomnia and the Hypersomnias - p. 177 24. Chapter 20: Drug Therapy for Managing Obesity and Eating Disorders - p. 185 25. Chapter 21: Treatment of Seizure Disorders - p. 191 26. Chapter 22: Drug Therapy for Spasticity Disorders - p. 206 27. Chapter 23: Ethanol, Other Alcohols, and Medications for Alcohol Use Disorder - p. 212 28. Chapter 24: Psychoactive Compounds and Substance Use Disorder - p. 222 29. Section 4: Drug Therapy for Pain Management - p. 235 30. Chapter 25: Introduction - p. 235 31. Chapter 26: General Anesthetics - p. 240 32. Chapter 27: Local Anesthetics - p. 251 33. Chapter 28: Opioid Analgesics - p. 259 34. Chapter 29: Nonsteroidal Antiinflammatory Drugs and Acetaminophen - p. 268 35. Chapter 30: Cannabinoids - p. 276 36. Chapter 31: Drug Therapy for Migraine Headache - p. 283 37. Section 5: Treatment of Inflammatory, Allergic and Immunologic Disorders - p. 291 38. Chapter 32: Drug Therapy for Gout and Hyperuricemia - p. 291 39. Chapter 33: Pharmacological Interventions for Allergic Reactions - p. 297 40. Chapter 34: Immunosuppressants for Autoimmune Disorders and Organ Transplantation - p. 305 41. Chapter 35: Drug Therapy for Rheumatoid Arthritis - p. 313 42. Section 6: Drug Treatment for Cardiovascular Diseases - p. 320 43. Chapter 36: Introduction to the Regulation of Cardiovascular Function - p. 320 44. Chapter 37: Overview of Hypertension Management and Drugs That Decrease Sympathetic Tone - p. 326 45. Chapter 38: Diuretics and Drugs That Affect Volume and Electrolyte Content - p. 332 46. Chapter 39: Drugs Affecting the Renin-Angiotensin-Aldosterone System - p. 347 47. Chapter 40: Calcium-Channel Blockers - p. 353 48. Chapter 41: Vasodilators for Hypertensive Crises, Pulmonary Hypertension, and Erectile Dysfunction - p. 358 49. Chapter 42: Treatment of Hyperlipidemias and Atherosclerotic Cardiovascular Disease - p. 366 50. Chapter 43: Treatment of Myocardial Ischemia and Angina Pectoris - p. 377 51. Chapter 44: Treatment of Heart Failure - p. 383 52. Chapter 45: Antiarrhythmic Drugs - p. 391 53. Chapter 46: Anticoagulant, Antiplatelet, and Fibrinolytic Medications - p. 405 54. Chapter 47: Drug Therapy for Hemophilia and the Deficiency Anemias - p. 415 55. Section 7: Treatment of Endocrine Disorders - p. 422 56. Chapter 48: Introduction to Endocrine Pharmacology - p. 422 57. Chapter 49: Treatment of Hypothalamic and Pituitary Disorders - p. 427 58. Chapter 50: Diagnosis and Treatment of Adrenocorticosteroid Disorders - p. 436 59. Chapter 51: Female Hormone Regulation - p. 445 60. Chapter 52: Androgens, Antiandrogens, and Their Clinical Uses - p. 461 61. Chapter 53: Drug Therapy for the Management of Diabetes - p. 468 62. Chapter 54: Drug Therapy for the Management of Thyroid Disorders - p. 484 63. Chapter 55: Calcium Regulating Hormones and Other Agents Affecting Bone - p. 493 64. Section 8: Chemotherapy - p. 503 65. Infectious Diseases - p. 503 66. Chapter 56: Principles of Antimicrobial Use - p. 503 67. Chapter 57: Drugs Targeting Bacterial Cell Walls and Membranes - p. 520 68. Chapter 58: Drugs Targeting Bacterial Protein Synthesis - p. 536 69. Chapter 59: Drugs Targeting Bacterial DNA - p. 550 70. Chapter 60: Antimycobacterial Agents - p. 559 71. Chapter 61: Drugs Targeting Resistant Organisms - p. 568 72. Parasitic Diseases - p. 574 73. Chapter 62: Antifungal Agents - p. 574 74. Chapter 63: Antimalarial and Other Antiprotozoal Agents - p. 584 75. Chapter 64: Anthelmintics and Ectoparasiticides - p. 595 76. Viruses - p. 601 77. Chapter 65: Antiviral Agents - p. 601 78. Chapter 66: Antiretroviral Drugs for HIV - p. 612 79. Cancer - p. 622 80. Chapter 67: Principles of Cancer and Antineoplastic Drug Use - p. 622 81. Chapter 68: Cytotoxic Agents - p. 631 82. Chapter 69: Targeted Anticancer Agents - p. 650 83. Chapter 70: Immunological and Cell-Based Therapies - p. 662 84. Section 9: Special Considerations - p. 670 85. Chapter 71: Therapeutic Use of Hematopoietic Growth Factors - p. 670 86. Chapter 72: Gastrointestinal Disorders and Their Treatment - p. 676 87. Chapter 73: Pharmacological Interventions for Asthma and Chronic Obstructive Pulmonary Disorders - p. 687 88. Chapter 74: Dietary Supplements, Nutraceuticals, and Natural Products - p. 698 89. Chapter 75: Essentials of Toxicology - p. 705 90. Chapter 76: Therapeutic Considerations for Pregnant, Pediatric, Geriatric, and Obese Individuals - p. 710 91. Appendix - p. 715 92. Index - p. 728 93. Confidence is ClinicalKey - p. 728
