Immunological Concepts in Transfusion Medicine provides a thorough discussion of the immune aspects of blood component transfusion, with in-depth information on the intricacies of immune responses to blood components and the immune processes that may be initiated in response to blood exposure. Written to increase knowledge and awareness of immune challenges such as alloimmunization and transfusion-related acute lung injury, this title bridges current basic scientific discoveries and the potential effects seen in blood recipients.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of Contributors - p. v 6. Preface - p. ix 7. Chapter 1. A Focused Review of Basic Immunology Concepts - p. 1 8. Chapter 2. Methods of RBC Alloimmunization to ABO and Non-ABO Antigens, and Test Methodologies - p. 15 9. Chapter 3. Autoimmunity: Cold and Warm Autoantibodies and Autoimmune Hemolytic Anemia - p. 35 10. Chapter 4. Allergic Transfusion Reactions - p. 45 11. Chapter 5. Changing Landscaping in Transfusion-Transmitted Infections - p. 55 12. Chapter 6. Transfusion-Related Immunomodulation - p. 81 13. Chapter 7. Transfusion-Related Acute Lung Injury - p. 97 14. Chapter 8. Alloantibodies and Platelets - p. 117 15. Chapter 9. Alloimmunization in Pregnancy - p. 149 16. Chapter 10. Immune-Mediated Cytopenia in the Pediatric Setting - p. 167 17. Chapter 11. Alloimmunization in Chronically Transfused Patients and Those With Malignancies - p. 183 18. Chapter 12. Graft-Versus-Host Disease and Transfusion-Associated Graft-Versus-Host Disease - p. 197 19. Chapter 13. Complications of ABO- and Non-ABO-incompatible Stem Cell Transplantations - p. 205 20. Chapter 14. Complications of Haploidentical and Mismatched HSC Transplantation - p. 223 21. Chapter 15. Therapeutic Apheresis - p. 239 22. Chapter 16. Passive Monoclonal and Polyclonal Antibody Therapies - p. 251 23. Passive Polyclonal Antibodies Therapy - p. 251 24. Passive Monoclonal Antibody Treatment - p. 258 25. Types of Illness Treated - p. 258 26. Autoimmune/Inflammatory Diseases - p. 261 27. Neurologic Diseases - p. 328 28. Allergic Diseases - p. 329 29. Coagulopathy and Other Benign Hematologic Diseases - p. 330 30. Infections - p. 330 31. Immunomodulation - p. 331 32. Metabolic Syndromes - p. 332 33. Endocrine Disorders - p. 332 34. Other Clinical Disorders - p. 332 35. Potential Future Uses of Monoclonal Antibodies and Their Targets - p. 332 36. Chapter 17. Chimeric Antigen Receptor Therapies - p. 349 37. Index - p. 361
Immunological Concepts in Transfusion Medicine provides a thorough discussion of the immune aspects of blood component transfusion, with in-depth information on the intricacies of immune responses to blood components and the immune processes that may be initiated in response to blood exposure. Written to increase knowledge and awareness of immune challenges such as alloimmunization and transfusion-related acute lung injury, this title bridges current basic scientific discoveries and the potential effects seen in blood recipients.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of Contributors - p. v 6. Preface - p. ix 7. Chapter 1. A Focused Review of Basic Immunology Concepts - p. 1 8. Chapter 2. Methods of RBC Alloimmunization to ABO and Non-ABO Antigens, and Test Methodologies - p. 15 9. Chapter 3. Autoimmunity: Cold and Warm Autoantibodies and Autoimmune Hemolytic Anemia - p. 35 10. Chapter 4. Allergic Transfusion Reactions - p. 45 11. Chapter 5. Changing Landscaping in Transfusion-Transmitted Infections - p. 55 12. Chapter 6. Transfusion-Related Immunomodulation - p. 81 13. Chapter 7. Transfusion-Related Acute Lung Injury - p. 97 14. Chapter 8. Alloantibodies and Platelets - p. 117 15. Chapter 9. Alloimmunization in Pregnancy - p. 149 16. Chapter 10. Immune-Mediated Cytopenia in the Pediatric Setting - p. 167 17. Chapter 11. Alloimmunization in Chronically Transfused Patients and Those With Malignancies - p. 183 18. Chapter 12. Graft-Versus-Host Disease and Transfusion-Associated Graft-Versus-Host Disease - p. 197 19. Chapter 13. Complications of ABO- and Non-ABO-incompatible Stem Cell Transplantations - p. 205 20. Chapter 14. Complications of Haploidentical and Mismatched HSC Transplantation - p. 223 21. Chapter 15. Therapeutic Apheresis - p. 239 22. Chapter 16. Passive Monoclonal and Polyclonal Antibody Therapies - p. 251 23. Passive Polyclonal Antibodies Therapy - p. 251 24. Passive Monoclonal Antibody Treatment - p. 258 25. Types of Illness Treated - p. 258 26. Autoimmune/Inflammatory Diseases - p. 261 27. Neurologic Diseases - p. 328 28. Allergic Diseases - p. 329 29. Coagulopathy and Other Benign Hematologic Diseases - p. 330 30. Infections - p. 330 31. Immunomodulation - p. 331 32. Metabolic Syndromes - p. 332 33. Endocrine Disorders - p. 332 34. Other Clinical Disorders - p. 332 35. Potential Future Uses of Monoclonal Antibodies and Their Targets - p. 332 36. Chapter 17. Chimeric Antigen Receptor Therapies - p. 349 37. Index - p. 361
