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This issue of Clinics in Laboratory Medicine, guest edited by Dr. Indira Guleria, will focus on New Pipeline of Immunoregulatory Molecules and Biomarkers in Transplantation. Topics include, but are not limited to, T Regulatory cells in Stem cells and Solid organ transplantation, Genetic Polymorphism in Cytokines and Costimulatory Molecules in Stem Cell and Solid Organ Transplantation, microRNAs and Transplantation, Role of B Regulatory Cells in Transplant Tolerance, Complement Activation, Biomarkers in Stem Cell Transplantation, Biomarkers of Transplant Tolerance at the Fetomaternal Interface, Signaling molecules in Transplantation and Post-Transplantation Cancer, Donor specific HLA antibodies as Biomarkers of Transplant Rejection, Novel Targets of Immunosuppression in Transplantation, Nanotechnology and Immune therapies in Transplantation, Role of Costimulatory Pathways in Transplant Tolerance, and Microbiota and Immune system and Implications.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Regulatory T Cells for More Targeted Immunosuppressive Therapies - p. 1 9. Regulatory and Effector B Cells: A New Path Toward Biomarkers and Therapeutic Targets to Improve Transplant Outcomes? - p. 15 10. Complement and Transplantation: From New Mechanisms to Potential Biomarkers and Novel Treatment Strategies - p. 31 11. Donor-Specific HLA Antibodies as Biomarkers of Transplant Rejection - p. 45 12. Biomarkers for Early Complications After Hematopoietic Stem Cell Transplantation - p. 61 13. Biomarkers in Solid Organ Transplantation - p. 73 14. The Role of Costimulatory Pathways in Transplant Tolerance - p. 87 15. Genetic Polymorphism in Cytokines and Costimulatory Molecules in Stem Cell and Solid Organ Transplantation - p. 107 16. MicroRNAs and Transplantation - p. 125 17. Biomarkers in Fetomaternal Tolerance - p. 145 18. Novel Targets of Immunosuppression in Transplantation - p. 157 19. Signaling Molecules in Posttransplantation Cancer - p. 171 20. Immunologic Effects of the Microbiota in Organ Transplantation - p. 185

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This issue of Clinics in Laboratory Medicine, guest edited by Dr. Indira Guleria, will focus on New Pipeline of Immunoregulatory Molecules and Biomarkers in Transplantation. Topics include, but are not limited to, T Regulatory cells in Stem cells and Solid organ transplantation, Genetic Polymorphism in Cytokines and Costimulatory Molecules in Stem Cell and Solid Organ Transplantation, microRNAs and Transplantation, Role of B Regulatory Cells in Transplant Tolerance, Complement Activation, Biomarkers in Stem Cell Transplantation, Biomarkers of Transplant Tolerance at the Fetomaternal Interface, Signaling molecules in Transplantation and Post-Transplantation Cancer, Donor specific HLA antibodies as Biomarkers of Transplant Rejection, Novel Targets of Immunosuppression in Transplantation, Nanotechnology and Immune therapies in Transplantation, Role of Costimulatory Pathways in Transplant Tolerance, and Microbiota and Immune system and Implications.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Regulatory T Cells for More Targeted Immunosuppressive Therapies - p. 1 9. Regulatory and Effector B Cells: A New Path Toward Biomarkers and Therapeutic Targets to Improve Transplant Outcomes? - p. 15 10. Complement and Transplantation: From New Mechanisms to Potential Biomarkers and Novel Treatment Strategies - p. 31 11. Donor-Specific HLA Antibodies as Biomarkers of Transplant Rejection - p. 45 12. Biomarkers for Early Complications After Hematopoietic Stem Cell Transplantation - p. 61 13. Biomarkers in Solid Organ Transplantation - p. 73 14. The Role of Costimulatory Pathways in Transplant Tolerance - p. 87 15. Genetic Polymorphism in Cytokines and Costimulatory Molecules in Stem Cell and Solid Organ Transplantation - p. 107 16. MicroRNAs and Transplantation - p. 125 17. Biomarkers in Fetomaternal Tolerance - p. 145 18. Novel Targets of Immunosuppression in Transplantation - p. 157 19. Signaling Molecules in Posttransplantation Cancer - p. 171 20. Immunologic Effects of the Microbiota in Organ Transplantation - p. 185

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