Studies in Natural Products Chemistry, Volume 64, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented.
1. Cover image - p. page_i 2. Title page - p. page_i 3. Table of Contents - p. page_i 4. Copyright - p. page_iv 5. Contributors - p. page_xiii 6. Preface - p. page_xvii 7. Chapter 1: The C-19 methyl substituted sarpagine-macroline-ajmaline alkaloids: Diversity, occurrence, bioactivity, and synthesis - p. page_xviii 8. Chapter 2: Recent progress in the synthesis of antimalarial indoloquinoline natural products and analogues - p. page_57 9. Chapter 3: Anticancer activity of natural coumarins for biological targets - p. page_84 10. Chapter 4: Silymarin compounds: Chemistry, innovative extraction techniques and synthesis - p. page_109 11. Chapter 5: The olive-tree leaves as a source of high-added value molecules: Oleuropein - p. page_130 12. Chapter 6: Progress in studies on meroterpenoids - p. page_180 13. Chapter 7: Effects of dietary n-3 polyunsaturated fatty acids on cardiovascular disease - p. page_216 14. Chapter 8: Potential of natural bioactive C-glycosyl flavones for antidiabetic properties - p. page_240 15. Chapter 9: Natural products encompassing antituberculosis activities - p. page_261 16. Chapter 10: Physiological effects of carotenoids on hyperglycemia and associated events - p. page_301 17. Chapter 11: Pharmacophore modeling and virtual screening for the discovery of biologically active natural products - p. page_320 18. Chapter 12: Formation of three-dimensional polymer structures through radical and ionic reactions of peroxychitosan - p. page_364 19. Chapter 13: Bioactive natural products as potent inhibitors of xanthine oxidase - p. page_390 20. Chapter 14: Organocatalyzed α-aminooxylation/amination of aldehydes and their sequential reactions: A versatile tool for the synthesis of bioactive molecules - p. page_416 21. Chapter 15: Bioactive compounds of Streptomyces: Biosynthesis to applications - p. page_465 22. Index - p. page_493
Studies in Natural Products Chemistry, Volume 64, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented.
1. Cover image - p. page_i 2. Title page - p. page_i 3. Table of Contents - p. page_i 4. Copyright - p. page_iv 5. Contributors - p. page_xiii 6. Preface - p. page_xvii 7. Chapter 1: The C-19 methyl substituted sarpagine-macroline-ajmaline alkaloids: Diversity, occurrence, bioactivity, and synthesis - p. page_xviii 8. Chapter 2: Recent progress in the synthesis of antimalarial indoloquinoline natural products and analogues - p. page_57 9. Chapter 3: Anticancer activity of natural coumarins for biological targets - p. page_84 10. Chapter 4: Silymarin compounds: Chemistry, innovative extraction techniques and synthesis - p. page_109 11. Chapter 5: The olive-tree leaves as a source of high-added value molecules: Oleuropein - p. page_130 12. Chapter 6: Progress in studies on meroterpenoids - p. page_180 13. Chapter 7: Effects of dietary n-3 polyunsaturated fatty acids on cardiovascular disease - p. page_216 14. Chapter 8: Potential of natural bioactive C-glycosyl flavones for antidiabetic properties - p. page_240 15. Chapter 9: Natural products encompassing antituberculosis activities - p. page_261 16. Chapter 10: Physiological effects of carotenoids on hyperglycemia and associated events - p. page_301 17. Chapter 11: Pharmacophore modeling and virtual screening for the discovery of biologically active natural products - p. page_320 18. Chapter 12: Formation of three-dimensional polymer structures through radical and ionic reactions of peroxychitosan - p. page_364 19. Chapter 13: Bioactive natural products as potent inhibitors of xanthine oxidase - p. page_390 20. Chapter 14: Organocatalyzed α-aminooxylation/amination of aldehydes and their sequential reactions: A versatile tool for the synthesis of bioactive molecules - p. page_416 21. Chapter 15: Bioactive compounds of Streptomyces: Biosynthesis to applications - p. page_465 22. Index - p. page_493
